PMID- 28763173 OWN - NLM STAT- MEDLINE DCOM- 20171121 LR - 20171128 IS - 1066-2936 (Print) IS - 1066-2936 (Linking) VI - 43 IP - 4 DP - 2016 Jul-Aug TI - Treatment of hyperoxic acute lung injury with stem cell transplantation in murine models: a brief review. PG - 437-445 AB - Hyperoxia has been a prominent clinical concern with the emergence of the intensive care unit and prolonged mechanical ventilation, along with the increasing use of hyperbaric oxygen therapy. Indeed, prolonged breathing of a high oxygen partial pressure may cause hyperoxic acute lung injury (HALI). To date, HALI has been a focus in the fields of pediatric and pulmonary medicine. However, no effective strategies have been developed for therapy for HALI due to the complicated mechanisms underlying the pathogenesis of HALI. In recent years, increasing studies have employed cell-based therapy for HALI. In this review, we summarize findings from available studies on therapy for HALI using stem cells in murine models and, based on concerns in this field, present our findings on cell-based therapy for HALI. CI - Copyright(c) Undersea and Hyperbaric Medical Society. FAU - Zhang, Hongmei AU - Zhang H AD - Department of Pathology, the First Hospital of Jining City, No 6, Jiankang Road, Jining City, Shandong, 272011, P. R. China. FAU - Zhang, Peixi AU - Zhang P AD - Department of Cardiothoracic Surgery, the First Hospital of Jining City, No 6, Jiankang Road, Jining City, Shandong, 272011, P. R. China. FAU - Han, Cuihong AU - Han C AD - Department of Pathology, the First Hospital of Jining City, No 6, Jiankang Road, Jining City, Shandong, 272011, P. R. China. FAU - Zhou, Fengjuan AU - Zhou F AD - Department of Pathology, the First Hospital of Jining City, No 6, Jiankang Road, Jining City, Shandong, 272011, P. R. China. FAU - Li, Liang AU - Li L AD - Department of Pathology, the First Hospital of Jining City, No 6, Jiankang Road, Jining City, Shandong, 272011, P. R. China. FAU - Liu, Wenwu AU - Liu W AD - Department of Diving and Hyperbaric Medicine, Secondary Military Medical University, No 800, Xiangyin Road, Yangpu District, Shanghai, 200433, P. R. China. LA - eng PT - Journal Article PT - Review PL - United States TA - Undersea Hyperb Med JT - Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc JID - 9312954 SB - IM MH - Acute Lung Injury/etiology/*therapy MH - Animals MH - Disease Models, Animal MH - Female MH - Hyperbaric Oxygenation/*adverse effects MH - Hyperoxia/*complications MH - Mice MH - Partial Pressure MH - Stem Cell Transplantation/adverse effects/*methods MH - Time Factors OTO - NOTNLM OT - hyperoxic lung injury OT - stem cell transplantation COIS- The authors of this paper declare no conflicts of interest exist with this submission. EDAT- 2016/04/01 00:00 MHDA- 2017/11/29 06:00 CRDT- 2017/08/02 06:00 PHST- 2017/08/02 06:00 [entrez] PHST- 2016/04/01 00:00 [pubmed] PHST- 2017/11/29 06:00 [medline] PST - ppublish SO - Undersea Hyperb Med. 2016 Jul-Aug;43(4):437-445.