PMID- 28763924 OWN - NLM STAT- MEDLINE DCOM- 20190208 LR - 20190215 IS - 0253-9624 (Print) IS - 0253-9624 (Linking) VI - 51 IP - 8 DP - 2017 Aug 6 TI - [Association between the time of sedentary behaviors and risk of type 2 diabetes]. PG - 734-739 LID - 10.3760/cma.j.issn.0253-9624.2017.08.014 [doi] AB - Objective: To explore the relationship between the time of sedentary behaviors and the risk of type 2 diabetes mellitus (T2DM) among rural adults in Henan Province. Methods: A total of 1 227 adults from Houzhai village in Zhengzhou City and Qiaomiao village in Jiaozuo City in Henan Province were randomly selected to participate in the survey; each of them finished a questionnaire and accepted physical examination and test of biochemical indicators. The participants were divided into case and control groups according to whether suffering from T2DM. A Pearson linear correlation and linear regression model analysis were used to investigate the relevance between the time of sedentary behaviors and fasting plasma glucose (FPG); meanwhile, a multi factor logistic regression model was used to analyze the relationship between the time of sedentary behaviors and T2DM. Results: The average FPG level among the participants was (5.4+/-2.5) mmol/L, and the average time of sedentary behaviors was (234.5+/-156.5) min per day. The prevalence rate of T2DM in subgroups whose time of sedentary behaviors were separately 0-<2.5, 2.5-<4.5, 4.5-<6.5 and >/=6.5 h/day were 15.8% (72/457), 19.3% (73/379), 16.7% (35/210) and 20.4% (37/181), respectively. There was a linear regression relationship between the time of sedentary behaviors(x) and FPG(y), the regression equation was: y=5.081+0.001x (t=3.01, P=0.003). Logistic regression model analysis showed that participants whose time of sedentary behaviors >/=6.5 h/day had significantly higher risk of T2DM than those whose time of sedentary behaviors between 0-2.4 h/day (OR=1.77, 95%CI: 1.11-2.81) after age and gender adjusted. However, the associations only exist in males and adults >/=50 years old according to sex and age stratification. It showed that participants with sedentary time >/=6.5 h/day had significantly higher risk of T2DM than those with sedentary time between 0-<2.5 h/d, with the corresponding OR (95%CI) at 2.34 (1.21-4.52) and 2.22 (1.19-4.16), respectively. Conclusion: The prolonged sedentary time is a risk factor of type 2 diabetes. After stratification by gender and age, the correlation only found in males and adults aged >/=50 years old. FAU - Shi, Y Y AU - Shi YY AD - College of Public Health, Zhengzhou University, Zhengzhou 450000, China. FAU - Li, Y Q AU - Li YQ FAU - Wang, J J AU - Wang JJ FAU - Wang, C J AU - Wang CJ FAU - Zhao, J Z AU - Zhao JZ FAU - Yin, L AU - Yin L FAU - Fan, J J AU - Fan JJ FAU - Zhou, W AU - Zhou W FAU - Li, L L AU - Li LL LA - chi PT - Journal Article PL - China TA - Zhonghua Yu Fang Yi Xue Za Zhi JT - Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] JID - 7904962 SB - IM MH - China/epidemiology MH - Diabetes Mellitus, Type 2/*epidemiology MH - Female MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Risk Factors MH - *Sedentary Behavior MH - Time Factors OTO - NOTNLM OT - Case-control studies OT - Diabetes mellitus, type 2 OT - Time of sedentary behaviors EDAT- 2017/08/03 06:00 MHDA- 2019/02/09 06:00 CRDT- 2017/08/02 06:00 PHST- 2017/08/02 06:00 [entrez] PHST- 2017/08/03 06:00 [pubmed] PHST- 2019/02/09 06:00 [medline] AID - 10.3760/cma.j.issn.0253-9624.2017.08.014 [doi] PST - ppublish SO - Zhonghua Yu Fang Yi Xue Za Zhi. 2017 Aug 6;51(8):734-739. doi: 10.3760/cma.j.issn.0253-9624.2017.08.014.