PMID- 28766047
OWN - NLM
STAT- MEDLINE
DCOM- 20180716
LR  - 20181113
IS  - 1615-2573 (Electronic)
IS  - 0910-8327 (Linking)
VI  - 33
IP  - 1
DP  - 2018 Jan
TI  - Prognostic value of cardiovascular magnetic resonance imaging for 
      life-threatening arrhythmia detected by implantable cardioverter-defibrillator in 
      Japanese patients with hypertrophic cardiomyopathy.
PG  - 49-57
LID - 10.1007/s00380-017-1030-3 [doi]
AB  - Implantable cardioverter-defibrillator (ICD) is effective to prevent sudden death 
      in HCM patients. We reviewed ICD records to analyze the relation between 
      life-threatening arrhythmia and late gadolinium enhancement (LGE) on 
      cardiovascular magnetic resonance (CMR) in Japanese hypertrophic cardiomyopathy 
      (HCM) patients. In 102 consecutive patients (median age 63 years, 63 males) 
      implanted with an ICD after CMR with gadolinium enhancement (median follow-up 
      2.8 years), the outcome of life-threatening arrhythmic events (appropriate ICD 
      interventions for ventricular tachycardia or ventricular fibrillation) was 
      examined. Appropriate interventions rate were 10.3% per year for secondary 
      prevention and 7.4% per year for primary prevention. The annualized ICD-related 
      complication rate was 3.7%. 43/91 patients (47%) implanted ICD for primary 
      prevention had maximum wall thickness >/=20 mm plus LGE in >/=4 of 17 left 
      ventricular segments (cut-off value obtained from ROC curve); the appropriate ICD 
      intervention rate was significantly higher in this group than in other patients 
      group (annualized event rate, 11.1 vs. 4.6%; log-rank P = 0.038). A combination 
      of myocardial hypertrophy and LGE is a useful outcome predictive factor for 
      life-threatening ventricular arrhythmia in Japanese HCM patients.
FAU - Hen, Yasuki
AU  - Hen Y
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan. yhen@shi.heart.or.jp.
FAU - Tsugu-Yagawa, Mayuko
AU  - Tsugu-Yagawa M
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan.
FAU - Iguchi, Nobuo
AU  - Iguchi N
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan.
FAU - Utanohara, Yuko
AU  - Utanohara Y
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan.
FAU - Takada, Kaori
AU  - Takada K
AD  - Department of Radiology, Sakakibara Heart Institute, Fuchu, Japan.
FAU - Machida, Haruhiko
AU  - Machida H
AD  - Department of Radiology, Tokyo Women's Medical University Medical Center East, 
      Tokyo, Japan.
FAU - Takara, Ayako
AU  - Takara A
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan.
FAU - Teraoka, Kunihiko
AU  - Teraoka K
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan.
FAU - Inoue, Kanki
AU  - Inoue K
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan.
FAU - Takamisawa, Itaru
AU  - Takamisawa I
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan.
FAU - Takayama, Morimasa
AU  - Takayama M
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan.
FAU - Yoshikawa, Tsutomu
AU  - Yoshikawa T
AD  - Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, 
      Tokyo, 183-0003, Japan.
LA  - eng
PT  - Journal Article
DEP - 20170801
PL  - Japan
TA  - Heart Vessels
JT  - Heart and vessels
JID - 8511258
SB  - IM
MH  - Aged
MH  - Cardiomyopathy, Hypertrophic/*complications/diagnosis/epidemiology
MH  - *Defibrillators, Implantable
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Ventricles/*diagnostic imaging/physiopathology
MH  - Humans
MH  - Incidence
MH  - Japan/epidemiology
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Retrospective Studies
MH  - Risk Assessment/*methods
MH  - Risk Factors
MH  - Survival Rate/trends
MH  - Tachycardia, Ventricular/*diagnosis/epidemiology/etiology
OTO - NOTNLM
OT  - Cardiac magnetic resonance
OT  - Hypertrophic cardiomyopathy
OT  - Implantable cardioverter-defibrillator
OT  - Late gadolinium enhancement
OT  - Ventricular arrhythmia
EDAT- 2017/08/03 06:00
MHDA- 2018/07/17 06:00
CRDT- 2017/08/03 06:00
PHST- 2017/04/11 00:00 [received]
PHST- 2017/07/28 00:00 [accepted]
PHST- 2017/08/03 06:00 [pubmed]
PHST- 2018/07/17 06:00 [medline]
PHST- 2017/08/03 06:00 [entrez]
AID - 10.1007/s00380-017-1030-3 [pii]
AID - 10.1007/s00380-017-1030-3 [doi]
PST - ppublish
SO  - Heart Vessels. 2018 Jan;33(1):49-57. doi: 10.1007/s00380-017-1030-3. Epub 2017 
      Aug 1.