PMID- 28773958 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1996-1944 (Print) IS - 1996-1944 (Electronic) IS - 1996-1944 (Linking) VI - 9 IP - 10 DP - 2016 Oct 15 TI - Physical Properties of PDMS (Polydimethylsiloxane) Microfluidic Devices on Fluid Behaviors: Various Diameters and Shapes of Periodically-Embedded Microstructures. LID - 10.3390/ma9100836 [doi] LID - 836 AB - Deformable polydimethylsiloxane (PDMS) microfluidic devices embedded with three differently-shaped obstacles (hexagon, square, and triangle) were used to examine the significant challenge to classical fluid dynamics. The significant factors in determining a quasi-steady state value of flow velocity (v)(QS) and pressure drop per unit length (∆P/∆x)(QS) were dependent on the characteristic of embedded microstructures as well as the applied flow rates. The deviation from the theoretical considerations due to PDMS bulging investigated by the friction constant and the normalized friction factor revealed that the largest PDMS bulging observed in hexagonal obstacles had the smallest (∆P/∆x)(QS) ratios, whereas triangle obstacles exhibited the smallest PDMS bulging, but recorded the largest (∆P/∆x)(QS) ratios. However, the influence of (v)(QS) ratio on microstructures was not very significant in this study. The results were close to the predicted values even though some discrepancy may be due to the relatively mean bulging and experimental uncertainty. The influence of deformable PDMS microfluidic channels with various shapes of embedded microstructures was compared with the rigid microchannels. The significant deviation from the classical relation (i.e., f~1/Re) was also observed in hexagonal obstacles and strongly dependent on the channel geometry, the degree of PDMS deformation, and the shapes of the embedded microstructures. FAU - Roh, Changhyun AU - Roh C AD - Biotechnology Research Division, Advanced Radiation Technology Institute (ARTI), Korea Atomic Energy Research Institute (KAERI), 29 Geumgu-gil, Jeongeup, Jeonbuk 56212, Korea. chroh@kaeri.re.kr. FAU - Lee, Jaewoong AU - Lee J AD - Department of Textile Engineering and Technology, Yeungnam University, 280 Daehak-Ro, Gyeongsan, Gyeongbuk 38541, Korea. jaewlee@yu.ac.kr. FAU - Kang, ChanKyu AU - Kang C AD - Ministry of Employment and Labor, Major Industrial Accident Prevention Center, 34 Yeosusandallo, Yeosu-Si, Jeonnam 59631, Korea. chemnet75@korea.kr. LA - eng PT - Journal Article DEP - 20161015 PL - Switzerland TA - Materials (Basel) JT - Materials (Basel, Switzerland) JID - 101555929 PMC - PMC5456639 OTO - NOTNLM OT - PDMS bulging OT - embedded microstructures OT - friction factor OT - hydraulic diameter OT - pressure drop COIS- The authors declare no conflict of interest. EDAT- 2017/08/05 06:00 MHDA- 2017/08/05 06:01 PMCR- 2016/10/15 CRDT- 2017/08/05 06:00 PHST- 2016/08/17 00:00 [received] PHST- 2016/09/29 00:00 [revised] PHST- 2016/10/11 00:00 [accepted] PHST- 2017/08/05 06:00 [entrez] PHST- 2017/08/05 06:00 [pubmed] PHST- 2017/08/05 06:01 [medline] PHST- 2016/10/15 00:00 [pmc-release] AID - ma9100836 [pii] AID - materials-09-00836 [pii] AID - 10.3390/ma9100836 [doi] PST - epublish SO - Materials (Basel). 2016 Oct 15;9(10):836. doi: 10.3390/ma9100836.