PMID- 28776172
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1092-8464 (Print)
IS  - 1092-8464 (Linking)
VI  - 19
IP  - 8
DP  - 2017 Aug
TI  - Optimization of Antiplatelet Therapy in STEMI.
PG  - 65
LID - 10.1007/s11936-017-0562-2 [doi]
AB  - Antiplatelet therapy is an essential component of ST elevation myocardial 
      infarction (STEMI) management. Dual antiplatelet therapy (DAPT) with aspirin and 
      clopidogrel has previously been the standard of care for STEMI management, but 
      the advent of newer, more potent P2Y12 inhibitors has expanded the options for 
      the management of STEMI. As compared with clopidogrel, these newer P2Y12 
      agents-such as prasugrel and ticagrelor-allow for further reductions in ischemic 
      end points, without the robust increases in bleeding seen in previous studies of 
      antithrombotic therapies. Understanding the nuances of these newer agents allows 
      optimization of therapy for the individual patient and circumstance. Ultimately, 
      combining these newer therapies, in specific populations, and specific 
      approaches-alternative access strategies (e.g., radial)-may allow us to maximize 
      efficacy and reduce the risk of antiplatelet therapies in treating patients with 
      STEMI.
FAU - Sinha, Abhishek
AU  - Sinha A
AD  - Cardiovascular Consultants Medical Group, Encino, CA, USA.
FAU - Agrawal, Kush
AU  - Agrawal K
AD  - Central Arizona Heart Specialists, Chandler, AZ, USA.
FAU - Sakhuja, Rahul
AU  - Sakhuja R
AD  - Cardiovascular Division, Massachusetts General Hospital and Harvard Medical 
      School, Boston, MA, USA. rsakhuja@partners.org.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Treat Options Cardiovasc Med
JT  - Current treatment options in cardiovascular medicine
JID - 9815942
OTO - NOTNLM
OT  - Antiplatelet therapy
OT  - DAPT
OT  - P2Y12 inhibitors
OT  - STEMI
EDAT- 2017/08/05 06:00
MHDA- 2017/08/05 06:01
CRDT- 2017/08/05 06:00
PHST- 2017/08/05 06:00 [entrez]
PHST- 2017/08/05 06:00 [pubmed]
PHST- 2017/08/05 06:01 [medline]
AID - 10.1007/s11936-017-0562-2 [pii]
AID - 10.1007/s11936-017-0562-2 [doi]
PST - ppublish
SO  - Curr Treat Options Cardiovasc Med. 2017 Aug;19(8):65. doi: 
      10.1007/s11936-017-0562-2.