PMID- 28780635 OWN - NLM STAT- MEDLINE DCOM- 20180307 LR - 20200306 IS - 1534-6285 (Electronic) IS - 1527-2737 (Linking) VI - 18 IP - 10 DP - 2017 Oct TI - Convective Radiofrequency Water Vapor Thermal Therapy with Rezum System. PG - 78 LID - 10.1007/s11934-017-0728-1 [doi] AB - PURPOSE: Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) are amongst the most commonly treated conditions by urologists. Minimally invasive therapies for the treatment of BPH/LUTS have garnered increased interest as new technology has emerged, improving durability, efficacy, and safety. This paper reviews the most recent literature regarding water vapor therapy, a convective thermal therapy that ablates prostatic tissue. RECENT FINDINGS: The current literature includes a pilot study of 65 men and a randomized controlled trial (RCT) of 197 men investigating the efficacy and safety profile of water vapor therapy up to 2 years. Subjects treated with water vapor therapy demonstrated a 51% reduction in IPSS from baseline, sustained at 24 months (p < 0.0001). Durable improvements in max flow rate (Qmax) and quality of life (QoL) were also achieved, while no changes in sexual function were observed. Reporting of adverse events (AEs) reveals predominantly Clavien grade I complications that were self-limited. The clinical efficacy and safety of water vapor therapy are durable to 24 months making it an attractive alternative for patients seeking a minimally invasive treatment for LUTS due to BPH. FAU - Helo, Sevann AU - Helo S AD - Division of Urology, Southern Illinois University School of Medicine, St. John's Pavilion, 301 North Eighth St., P.O. Box 19665, Springfield, IL, 62794-9665, USA. FAU - Holland, Bradley AU - Holland B AD - Division of Urology, Southern Illinois University School of Medicine, St. John's Pavilion, 301 North Eighth St., P.O. Box 19665, Springfield, IL, 62794-9665, USA. FAU - McVary, Kevin T AU - McVary KT AD - Division of Urology, Southern Illinois University School of Medicine, St. John's Pavilion, 301 North Eighth St., P.O. Box 19665, Springfield, IL, 62794-9665, USA. kmcvary@siumed.edu. LA - eng PT - Journal Article PT - Review PL - United States TA - Curr Urol Rep JT - Current urology reports JID - 100900943 RN - 0 (Steam) SB - IM MH - Ablation Techniques/instrumentation/*methods MH - Humans MH - Lower Urinary Tract Symptoms/etiology/*surgery MH - Male MH - Prostatic Hyperplasia/complications MH - Quality of Life MH - *Radiofrequency Therapy MH - *Steam/adverse effects OTO - NOTNLM OT - Lower urinary tract symptoms OT - Minimally invasive therapies OT - Prostate OT - Prostatic hyperplasia OT - Thermal conductivity EDAT- 2017/08/07 06:00 MHDA- 2018/03/08 06:00 CRDT- 2017/08/07 06:00 PHST- 2017/08/07 06:00 [entrez] PHST- 2017/08/07 06:00 [pubmed] PHST- 2018/03/08 06:00 [medline] AID - 10.1007/s11934-017-0728-1 [pii] AID - 10.1007/s11934-017-0728-1 [doi] PST - ppublish SO - Curr Urol Rep. 2017 Oct;18(10):78. doi: 10.1007/s11934-017-0728-1.