PMID- 28780802
OWN - NLM
STAT- MEDLINE
DCOM- 20190225
LR  - 20190225
IS  - 1001-9391 (Print)
IS  - 1001-9391 (Linking)
VI  - 35
IP  - 5
DP  - 2017 May 20
TI  - [A study on the effects of exposure to benzene on the activity of immunoglobulin 
      E].
PG  - 380-382
LID - 10.3760/cma.j.issn.1001-9391.2017.05.018 [doi]
AB  - Objective: To analyze the level of immunoglobulin E (IgE) changes with benzene 
      exposure workers. Methods: Firstly, through occupational health monitoring, 68 
      hospitalized cases were discovered who were suspected chronic benzene poisoning. 
      Secondly, according to the GBZ68-2013left angle bracket, doubleThe diagnosis of occupational benzene 
      poisoningright angle bracket, doublestandard diagnosis and indexing, 68 cases were divided into the benzene 
      poisoning group (n= 29) and the benzene exposure group (n=39) . 50 cases of 
      healthy workers without benzene exposure were for the control group. Use the 
      immune luminescence method to detect IgE levels. Thirdly, Case-control study was 
      used, observing IgE changes though the three groups by statistical analysis. 
      Results: Compared with control group, the level of leukocyte、neutrophil and IgE 
      was drop in benzene exposure group with statistically significant (P<0.05) . 
      Compared with benzene exposure group, IgE of benzene poisoning group was rise, 
      with statistically significant (P<0.05) , IgE of mild benzene poisoning group 
      rise the most obvious, with statistically significant (P<0.05) . Compared with 
      benzene exposure group, IgE of moderate benzene poisoning group was drop, without 
      statistically significant (P>0.05) . Conclusion: Benzene occupational exposure 
      can induce immunosuppression, IgE decreases, and reduces immune surveillance. The 
      response of the IgE level in the mild benzene poisoning patients was 
      significantly elevated, whether it is protective response of the body immune 
      function needs to be studied further investigated.
FAU - Zhang, Y L
AU  - Zhang YL
AD  - Guangzhou occupational disease prevention and treatment hospital, Guangdong 
      Guangzhou 510620, China.
FAU - Liu, W W
AU  - Liu WW
FAU - Zeng, W Y
AU  - Zeng WY
FAU - Lin, Q H
AU  - Lin QH
FAU - Liu, Y M
AU  - Liu YM
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
JT  - Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng 
      zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
JID - 8410840
RN  - 37341-29-0 (Immunoglobulin E)
RN  - J64922108F (Benzene)
SB  - IM
MH  - Benzene/*poisoning
MH  - Case-Control Studies
MH  - Chronic Disease
MH  - Humans
MH  - Immunoglobulin E/*metabolism
MH  - Occupational Exposure/*adverse effects
OTO - NOTNLM
OT  - Benzene exposure
OT  - Benzene poisoning
OT  - Immunoglobulin E (IgE)
EDAT- 2017/08/07 06:00
MHDA- 2019/02/26 06:00
CRDT- 2017/08/08 06:00
PHST- 2017/08/08 06:00 [entrez]
PHST- 2017/08/07 06:00 [pubmed]
PHST- 2019/02/26 06:00 [medline]
AID - 10.3760/cma.j.issn.1001-9391.2017.05.018 [doi]
PST - ppublish
SO  - Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2017 May 20;35(5):380-382. doi: 
      10.3760/cma.j.issn.1001-9391.2017.05.018.