PMID- 28781731
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240326
IS  - 2008-126X (Print)
IS  - 2228-7442 (Electronic)
IS  - 2008-126X (Linking)
VI  - 8
IP  - 3
DP  - 2017 May-Jun
TI  - Neuropsychological Functioning in Obsessive-Compulsive Washers: Drug-Naive 
      Without Depressive Symptoms.
PG  - 233-248
LID - 10.18869/nirp.bcn.8.3.233 [doi]
AB  - INTRODUCTION: Obsessive-Compulsive Disorder (OCD) is a complex and heterogeneous 
      neuropsychiatric syndrome. Contamination obsessions and washing/cleaning 
      compulsions are the most frequent clinical OCD subtypes. The current study aimed 
      at examining the neuropsychological impairments in drug-naive 
      obsessive-compulsive (OC) washers without depressive symptoms and their 
      association with the severity of symptoms. METHODS: In the current 
      causal-comparative study, 35 patients with diagnostic and statistical mental 
      disorders class (DSM)-IV diagnosed with washing-subtype OCD and 35 healthy 
      subjects were selected by the convenience sampling method and evaluated by 
      computerized neuropsychology battery and clinical tests as Stroop Color-Word Test 
      (SCWT), Wisconsin Card Sorting Test (WCST), Go/No-Go Test, Digits Forward (DF), 
      Digits Backward (DB), Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Beck 
      Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and General Health 
      Questionnaire (GHQ)-28. The patients were matched to the comparison group with 
      regard to age, gender, intelligence quotient (IQ), education, and handedness. All 
      the tests were standardized in Iran. SPSS version 20.00 was used for descriptive 
      and analytical data analysis. RESULTS: There was no statistically significant 
      different between the OCD washing and the control groups regarding 
      socio-demographic variables or IQ. There were significant differences between the 
      OC washer and the healthy control groups on the neuropsychological functioning. 
      The obtained results suggested that OC washers performed significantly worse on 
      neuropsychological measures than the controls. There was no significant 
      association between the severity of OC symptoms and the neuropsychological 
      functions in the OCD washing group. CONCLUSION: It was concluded that executive 
      function impairment, which is a core feature in OC washers was trait-like in 
      nature.
FAU - Saremi, Ali Akbar
AU  - Saremi AA
AD  - Department of Cognitive Neuroscience, Institute for Cognitive Science Studies 
      (ICSS), Tehran, Iran.
FAU - Shariat, Seyed Vahid
AU  - Shariat SV
AD  - Mental Health Research Center, Tehran Institute of Psychiatry, School of 
      Behavioural Sciences and Mental Health, Iran University of Medical Sciences, 
      Tehran, Iran.
FAU - Nazari, Mohammad Ali
AU  - Nazari MA
AD  - Department of Psychology, Faculty of Education & Psychology, University of 
      Tabriz, Tabriz, Iran.
FAU - Dolatshahi, Behrooz
AU  - Dolatshahi B
AD  - Department of Psychology, University of Social Welfare and Rehabilitation 
      Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Basic Clin Neurosci
JT  - Basic and clinical neuroscience
JID - 101575211
PMC - PMC5535329
OTO - NOTNLM
OT  - Neuropsychology
OT  - Obsessive-Compulsive Disorder
OT  - State-trait deficits
OT  - Washers
COIS- Conflict of Interest The authors declared no conflicts of interest.
EDAT- 2017/08/07 06:00
MHDA- 2017/08/07 06:01
PMCR- 2017/05/01
CRDT- 2017/08/08 06:00
PHST- 2017/08/08 06:00 [entrez]
PHST- 2017/08/07 06:00 [pubmed]
PHST- 2017/08/07 06:01 [medline]
PHST- 2017/05/01 00:00 [pmc-release]
AID - bcn-8-233 [pii]
AID - 10.18869/nirp.bcn.8.3.233 [doi]
PST - ppublish
SO  - Basic Clin Neurosci. 2017 May-Jun;8(3):233-248. doi: 10.18869/nirp.bcn.8.3.233.