PMID- 28787733
OWN - NLM
STAT- MEDLINE
DCOM- 20170905
LR  - 20181202
IS  - 1423-0097 (Electronic)
IS  - 1018-2438 (Linking)
VI  - 173
IP  - 3
DP  - 2017
TI  - Association between Caesarean Delivery and Isolated Doses of Formula Feeding in 
      Cow Milk Allergy.
PG  - 147-152
LID - 10.1159/000477725 [doi]
AB  - BACKGROUND: Cow milk allergy (CMA) is the most common food allergy in breastfed 
      infants. The aim of this study is to verify whether certain perinatal factors may 
      influence the development of CMA immunoglobulin E (IgE)+. METHODS: A 
      retrospective, observational study of case and control groups was carried out. 
      Information was collected of patients with CMA IgE+ from our department during 
      the years 1990-2013. Patients of the same age and sex were recruited for the 
      control group. Information on the following variables was collected: sex, age, 
      pregnancy tolerance, duration of pregnancy, type of delivery, isolated doses of 
      formula feeding in hospital (FFH), duration of breastfeeding, and family history 
      of allergy (defined as >/=1 first-degree family member with allergic disease). 
      Statistical analysis was performed using multivariate logistic regression 
      techniques. RESULTS: A total of 211 cases were included in this study. 
      Multivariate analysis showed an influence of duration of breastfeeding, FFH to be 
      a risk factor (OR 4.94; 95% CI 2.68-9.08), especially in caesarean delivery (OR 
      11.82; 95% CI 2.64-47.50), and prematurity (OR 0.29; 95% CI 0.09-0.92) to be a 
      protective factor. CONCLUSIONS: Perinatal factors play a key role in the 
      development of CMA IgE+, with an influence of breastfeeding duration, FFH and 
      caesarean delivery as risk factors and prematurity as a protective factor. While 
      family history had no important role, environmental factors were more decisive.
CI  - (c) 2017 S. Karger AG, Basel.
FAU - Gil, Francisco
AU  - Gil F
AD  - Department of Pediatrics, Estella Hospital, Estella, Spain.
FAU - Amezqueta, Ana
AU  - Amezqueta A
FAU - Martinez, Diana
AU  - Martinez D
FAU - Aznal, Elena
AU  - Aznal E
FAU - Etayo, Veronica
AU  - Etayo V
FAU - Dura, Teodoro
AU  - Dura T
FAU - Sanchez-Valverde, Felix
AU  - Sanchez-Valverde F
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20170809
PL  - Switzerland
TA  - Int Arch Allergy Immunol
JT  - International archives of allergy and immunology
JID - 9211652
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Breast Feeding
MH  - Cesarean Section
MH  - Child
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/immunology
MH  - Infant
MH  - Infant Formula/*statistics & numerical data
MH  - Male
MH  - Milk Hypersensitivity/*epidemiology/immunology
MH  - Pregnancy
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Spain
MH  - Young Adult
OTO - NOTNLM
OT  - Breastfeeding
OT  - Caesarean delivery
OT  - Cow milk allergy
OT  - Formula feeding
EDAT- 2017/08/09 06:00
MHDA- 2017/09/07 06:00
CRDT- 2017/08/09 06:00
PHST- 2017/01/12 00:00 [received]
PHST- 2017/05/23 00:00 [accepted]
PHST- 2017/08/09 06:00 [pubmed]
PHST- 2017/09/07 06:00 [medline]
PHST- 2017/08/09 06:00 [entrez]
AID - 000477725 [pii]
AID - 10.1159/000477725 [doi]
PST - ppublish
SO  - Int Arch Allergy Immunol. 2017;173(3):147-152. doi: 10.1159/000477725. Epub 2017 
      Aug 9.