PMID- 28790162
OWN - NLM
STAT- MEDLINE
DCOM- 20180508
LR  - 20180725
IS  - 1479-6821 (Electronic)
IS  - 1351-0088 (Linking)
VI  - 24
IP  - 10
DP  - 2017 Oct
TI  - The future: diagnostic and imaging advances in MEN1 therapeutic approaches and 
      management strategies.
PG  - T209-T225
LID - 10.1530/ERC-17-0231 [doi]
AB  - Prospective randomized data are lacking, but current clinical expert guidelines 
      recommend annual screening examinations, including laboratory assessments and 
      various imaging modalities (e.g. CT, MRI, scintigraphy and EUS) for patients with 
      multiple endocrine neoplasia type 1 (MEN1). Routine screening is proposed to 
      detect and localize neuroendocrine manifestations as early as possible. The goal 
      is timely intervention to improve quality of life and to increase life expectancy 
      by preventing the development of life-threatening hormonal syndromes and/or 
      metastatic disease. In recent years, some studies compared different and new 
      imaging methods regarding their sensitivity and utility in MEN1 patients. This 
      present article reviews the proposed diagnostic tools for MEN1 screening as well 
      as potential future perspectives.
CI  - (c) 2017 Society for Endocrinology.
FAU - Manoharan, Jerena
AU  - Manoharan J
AD  - Department of VisceralThoracic and Vascular Surgery, Philipps University Marburg, 
      Marburg, Germany jerena.manoharan@uk-gm.de.
FAU - Albers, Max B
AU  - Albers MB
AD  - Department of VisceralThoracic and Vascular Surgery, Philipps University Marburg, 
      Marburg, Germany.
FAU - Bartsch, Detlef K
AU  - Bartsch DK
AD  - Department of VisceralThoracic and Vascular Surgery, Philipps University Marburg, 
      Marburg, Germany.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20170808
PL  - England
TA  - Endocr Relat Cancer
JT  - Endocrine-related cancer
JID - 9436481
SB  - IM
MH  - Humans
MH  - Mass Screening
MH  - *Multiple Endocrine Neoplasia Type 1/diagnosis/diagnostic 
      imaging/pathology/therapy
MH  - *Neuroendocrine Tumors/diagnosis/diagnostic imaging/pathology/therapy
OTO - NOTNLM
OT  - diagnostic
OT  - imaging
OT  - multiple endocrine neoplasia type 1
OT  - screening
EDAT- 2017/08/10 06:00
MHDA- 2018/05/09 06:00
CRDT- 2017/08/10 06:00
PHST- 2017/07/29 00:00 [received]
PHST- 2017/08/08 00:00 [accepted]
PHST- 2017/08/10 06:00 [pubmed]
PHST- 2018/05/09 06:00 [medline]
PHST- 2017/08/10 06:00 [entrez]
AID - ERC-17-0231 [pii]
AID - 10.1530/ERC-17-0231 [doi]
PST - ppublish
SO  - Endocr Relat Cancer. 2017 Oct;24(10):T209-T225. doi: 10.1530/ERC-17-0231. Epub 
      2017 Aug 8.