PMID- 28798802
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 1741-427X (Print)
IS  - 1741-4288 (Electronic)
IS  - 1741-427X (Linking)
VI  - 2017
DP  - 2017
TI  - Prescribed Renoprotective Chinese Herbal Medicines Were Associated with a Lower 
      Risk of All-Cause and Disease-Specific Mortality among Patients with Chronic 
      Kidney Disease: A Population-Based Follow-Up Study in Taiwan.
PG  - 5632195
LID - 10.1155/2017/5632195 [doi]
LID - 5632195
AB  - Chinese herbal medicines (CHMs) containing aristolochic acid (AA) are associated 
      with chronic kidney disease (CKD), but some prescribed CHMs have been shown to 
      possess renoprotective effects. We conducted a nationwide retrospective cohort 
      study to delineate the role of prescribed CHMs on the CKD progression. 
      Renoprotective CHM (RPCHM) was defined if a CHM contained dong chong xia cao 
      (Cordyceps sinensis (Berk.) Sacc.), da huang (Rheum palmatum L), huang qi 
      (Astragalus membranaceus), dan shen (Salvia miltiorrhiza Bge.), and dong quai 
      (Angelica sinensis (Oliv.) Diels) or belonged to specific mixture herbal 
      formulations (Yishen capsule, Saireito, or Wen Pi Tang). Subjects who had ever 
      used AA-containing CHMs, had cancer or HIV prior to CKD diagnosis, or died within 
      the first month of CKD diagnosis were excluded. A total of 11,625 patients were 
      eligible subjects. The adjusted hazard ratio (aHR) for all-cause mortality was 
      0.6 (p < 0.001) and 0.6 (p = 0.013) among subjects receiving RPCHMs containing 
      Angelica sinensis and those receiving other RPCHMs, respectively. For CKD-related 
      mortality, the aHR among subjects receiving RPCHMs containing Angelica sinensis 
      was 0.6 (p = 0.025). The use of specific RPCHMs, especially those that contained 
      Angelica sinensis, was associated with a lower risk of mortality among CKD 
      patients.
FAU - Hsieh, Chuan-Fa
AU  - Hsieh CF
AD  - Department of Medical Education and Research, Taiwan Landseed Hospital, No. 77, 
      Guangtai Rd., Pingzhen Dist., Taoyuan 32449, Taiwan.
AD  - Center for General Education, Hsin Sheng College of Medical Care and Management, 
      No. 418, Zhongxing Rd., Longtan Dist., Taoyuan 32555, Taiwan.
FAU - Chang, Huan-Cheng
AU  - Chang HC
AD  - Division of Nephrology, Department of Medicine, Taiwan Landseed Hospital, No. 77, 
      Guangtai Rd., Pingzhen Dist., Taoyuan 32449, Taiwan.
AD  - Department of Health Care Management, Chang Gung University, No. 259, Wenhua 1st 
      Rd., Guishan Dist., Taoyuan 33302, Taiwan.
FAU - Huang, Song-Lih
AU  - Huang SL
AD  - Institute of Public Health & Department of Public Health, School of Medicine, 
      National Yang-Ming University, No. 155, Sec. 2, Linong St., Taipei 11221, Taiwan.
FAU - Chen, Chien-Lung
AU  - Chen CL
AUID- ORCID: 0000-0002-4986-2424
AD  - Division of Nephrology, Department of Medicine, Taiwan Landseed Hospital, No. 77, 
      Guangtai Rd., Pingzhen Dist., Taoyuan 32449, Taiwan.
AD  - Institute of Systems Biology and Bioinformatics, Department of Biomedical 
      Sciences and Engineering, National Central University, No. 300, Zhongda Rd., 
      Zhongli District, Taoyuan 32001, Taiwan.
FAU - Chen, Wei-Ta
AU  - Chen WT
AD  - Department of Chinese Medicine, Taiwan Landseed Hospital, No. 77, Guangtai Rd., 
      Pingzhen Dist., Taoyuan 32449, Taiwan.
FAU - Yang, Chen-Chang
AU  - Yang CC
AUID- ORCID: 0000-0003-1391-8323
AD  - Institute of Environmental & Occupational Health Sciences, School of Medicine, 
      National Yang-Ming University, No. 155, Sec. 2, Linong St., Taipei 11221, Taiwan.
AD  - Division of Clinical Toxicology & Occupational Medicine, Department of Medicine, 
      Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., Taipei 11217, 
      Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20170717
PL  - United States
TA  - Evid Based Complement Alternat Med
JT  - Evidence-based complementary and alternative medicine : eCAM
JID - 101215021
PMC - PMC5535732
EDAT- 2017/08/12 06:00
MHDA- 2017/08/12 06:01
PMCR- 2017/07/17
CRDT- 2017/08/12 06:00
PHST- 2017/02/10 00:00 [received]
PHST- 2017/06/06 00:00 [accepted]
PHST- 2017/08/12 06:00 [entrez]
PHST- 2017/08/12 06:00 [pubmed]
PHST- 2017/08/12 06:01 [medline]
PHST- 2017/07/17 00:00 [pmc-release]
AID - 10.1155/2017/5632195 [doi]
PST - ppublish
SO  - Evid Based Complement Alternat Med. 2017;2017:5632195. doi: 10.1155/2017/5632195. 
      Epub 2017 Jul 17.