PMID- 28806552
OWN - NLM
STAT- MEDLINE
DCOM- 20180814
LR  - 20180814
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 610-611
DP  - 2018 Jan 1
TI  - Exposure of engineered nanoparticles to Alexandrium tamarense (Dinophyceae): 
      Healthy impacts of nanoparticles via toxin-producing dinoflagellate.
PG  - 356-366
LID - S0048-9697(17)31277-9 [pii]
LID - 10.1016/j.scitotenv.2017.05.170 [doi]
AB  - Human activities can enhance the frequency, intensity and occurrence of harmful 
      algal blooms (HABs). Engineered nanoparticles (ENPs), contained in many 
      materials, will inevitably enter coastal waters and thus cause unpredictable 
      impacts on aquatic organisms. However, knowledge of the influence of ENPs on HAB 
      species is still lacking. In this study, we examined the effects of titanium 
      dioxide nanoparticles ((n)TiO(2)), zinc oxide nanoparticles ((n)ZnO) and aluminum 
      oxide nanoparticles ((n)Al(2)O(3)) on physiological changes and paralytic 
      shellfish poisoning toxins (PSTs) production of Alexandrium tamarense. We found a 
      dose-dependent decrease in photosynthetic activity of A. tamarense under all 
      three ENPs and a significant growth inhibition induced by (n)ZnO. The largest 
      reactive oxygen species (ROS) production was induced by (n)TiO(2), followed by 
      (n)ZnO and (n)Al(2)O(3). Moreover, the PSTs production rate increased by 3.9-fold 
      for (n)TiO(2) (p<0.01) and 4.5-fold for (n)Al(2)O(3) (p<0.01) at a concentration 
      of 200mgL(-1). The major component, C2 was transformed to its epimer C1 and the 
      proportion of decarbamoyl toxins increased under 200mgL(-1) of (n)ZnO and 
      (n)Al(2)O(3). In addition, the proportion of carbamate toxins increased upon 
      exposure to 2mgL(-1) ENPs, while decreased upon exposure to 200mgL(-1) ENPs. The 
      changes in PSTs production and composition might be an adaptive response for A. 
      tamarense to overcome the stress of ENPs exposure. This work brings the first 
      evidence that ENP would affect PSTs production and profiles.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Li, Manlu
AU  - Li M
AD  - Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China; School 
      of Environment, Tsinghua University, Beijing 100084, China.
FAU - Chen, Daoyi
AU  - Chen D
AD  - Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China; School 
      of Environment, Tsinghua University, Beijing 100084, China.
FAU - Liu, Yang
AU  - Liu Y
AD  - Key Laboratory of Marine Ecology and Environmental Sciences, Institute of 
      Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; University of 
      Chinese Academy of Sciences, Beijing 100039, China.
FAU - Chuang, Chia Ying
AU  - Chuang CY
AD  - Research Center for Environmental Changes, Academia Sinica, Taipei, Taiwan.
FAU - Kong, Fanzhou
AU  - Kong F
AD  - Key Laboratory of Marine Ecology and Environmental Sciences, Institute of 
      Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Laboratory of 
      Marine Ecology and Environmental Science, Qingdao National Laboratory for Marine 
      Science and Technology, Qingdao 266071, China.
FAU - Harrison, Paul J
AU  - Harrison PJ
AD  - Dept Earth & Ocean Sciences, University of British Columbia, Vancouver, BC, 
      Canada.
FAU - Zhu, Xiaoshan
AU  - Zhu X
AD  - Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China; School 
      of Environment, Tsinghua University, Beijing 100084, China.
FAU - Jiang, Yuelu
AU  - Jiang Y
AD  - Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China; School 
      of Environment, Tsinghua University, Beijing 100084, China. Electronic address: 
      jiang.yuelu@sz.tsinghua.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20170811
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Marine Toxins)
RN  - 15FIX9V2JP (titanium dioxide)
RN  - D1JT611TNE (Titanium)
RN  - LMI26O6933 (Aluminum Oxide)
RN  - SOI2LOH54Z (Zinc Oxide)
SB  - IM
MH  - Aluminum Oxide/pharmacology
MH  - Dinoflagellida/*drug effects
MH  - *Harmful Algal Bloom
MH  - Marine Toxins/*biosynthesis
MH  - Metal Nanoparticles/*chemistry
MH  - Titanium/pharmacology
MH  - Zinc Oxide/pharmacology
OTO - NOTNLM
OT  - Engineered nanoparticles
OT  - Growth
OT  - Paralytic shellfish poisoning toxins
OT  - Photosynthesis performance
OT  - Reactive oxygen species
EDAT- 2017/08/15 06:00
MHDA- 2018/08/15 06:00
CRDT- 2017/08/15 06:00
PHST- 2017/02/21 00:00 [received]
PHST- 2017/05/17 00:00 [revised]
PHST- 2017/05/19 00:00 [accepted]
PHST- 2017/08/15 06:00 [pubmed]
PHST- 2018/08/15 06:00 [medline]
PHST- 2017/08/15 06:00 [entrez]
AID - S0048-9697(17)31277-9 [pii]
AID - 10.1016/j.scitotenv.2017.05.170 [doi]
PST - ppublish
SO  - Sci Total Environ. 2018 Jan 1;610-611:356-366. doi: 
      10.1016/j.scitotenv.2017.05.170. Epub 2017 Aug 11.