PMID- 28807733
OWN - NLM
STAT- MEDLINE
DCOM- 20171003
LR  - 20171003
IS  - 1879-1891 (Electronic)
IS  - 0002-9394 (Linking)
VI  - 182
DP  - 2017 Oct
TI  - Early Trabeculotomy Ab Externo in Treatment of Sturge-Weber Syndrome.
PG  - 141-146
LID - S0002-9394(17)30335-5 [pii]
LID - 10.1016/j.ajo.2017.08.002 [doi]
AB  - PURPOSE: To evaluate the intermediate-term efficacy and safety of trabeculotomy 
      in infant Sturge-Weber syndrome (SWS). DESIGN: Retrospective cohort study. 
      METHODS: All SWS-induced glaucoma patients less than 12 months of age who 
      underwent trabeculotomy at our Ophthalmology Department from August 2011 to March 
      2017 were reviewed. Baseline demographics, intraocular pressure (IOP), 
      cup-to-disc ratio (C/D), and cornea diameters were noted before surgery. The IOP, 
      success probabilities, and medication usage were recorded during follow-up until 
      the last visit. RESULTS: Overall, 34 eyes (32 patients) were included, with a 
      median surgery age of 3 months and a median follow-up time of 15.5 months. The 
      mean preoperative IOP, asymmetry between 2 eyes, cornea diameter, and median C/D 
      were 21.5 +/- 6.6 mm Hg, 10.1 +/- 4.9 mm Hg, 12.6 +/- 0.7 mm, and 0.65 (interquartile 
      range [IQR]: 0.55, 0.80), respectively. The IOP was significantly reduced from 
      the preoperative baseline at 1 week, 3 months, 6 months, 1 year, and 2 years 
      after the surgery (P < .05). At the last follow-up, the cumulative proportions of 
      overall and complete success were 86.6% and 66.0%, respectively. Complications 
      included a transient shallow anterior chamber. Thirty of the 34 eyes had 
      intraoperative hyphema, 27 of which lasted less than 3 days. No other 
      complications were noted during the follow-up. CONCLUSIONS: Compared to previous 
      studies with a later diagnosis of glaucoma in SWS patients, better outcomes were 
      achieved with an early diagnosis of glaucoma in SWS patients. Early trabeculotomy 
      ab externo was safe and led to good intermediate-term surgical outcomes for 
      early-onset glaucoma in SWS patients. Higher preoperative IOP and corneal edema 
      were associated with a greater risk of surgery failure.
CI  - Copyright (c) 2017 Elsevier Inc. All rights reserved.
FAU - Wu, Yue
AU  - Wu Y
AD  - Department of Ophthalmology, Ninth People's Hospital Affiliated With Shanghai 
      Jiao Tong University School of Medicine, Shanghai, China.
FAU - Yu, Rujing
AU  - Yu R
AD  - Department of Ophthalmology, Ninth People's Hospital Affiliated With Shanghai 
      Jiao Tong University School of Medicine, Shanghai, China.
FAU - Chen, Di
AU  - Chen D
AD  - Department of Ophthalmology, Ninth People's Hospital Affiliated With Shanghai 
      Jiao Tong University School of Medicine, Shanghai, China.
FAU - Xu, Li
AU  - Xu L
AD  - Department of Ophthalmology, Ninth People's Hospital Affiliated With Shanghai 
      Jiao Tong University School of Medicine, Shanghai, China.
FAU - Zhu, Li
AU  - Zhu L
AD  - Department of Ophthalmology, Ninth People's Hospital Affiliated With Shanghai 
      Jiao Tong University School of Medicine, Shanghai, China.
FAU - Li, Mao
AU  - Li M
AD  - Department of Ophthalmology, Ninth People's Hospital Affiliated With Shanghai 
      Jiao Tong University School of Medicine, Shanghai, China.
FAU - Guo, Chunyu
AU  - Guo C
AD  - Department of Ophthalmology, Ninth People's Hospital Affiliated With Shanghai 
      Jiao Tong University School of Medicine, Shanghai, China.
FAU - Gu, Ping
AU  - Gu P
AD  - Department of Ophthalmology, Ninth People's Hospital Affiliated With Shanghai 
      Jiao Tong University School of Medicine, Shanghai, China.
FAU - Lin, Xiaoxi
AU  - Lin X
AD  - Department of Plastic and Reconstructive Surgery, Ninth People's Hospital 
      Affiliated With Shanghai Jiao Tong University School of Medicine, Shanghai, 
      China.
FAU - Guo, Wenyi
AU  - Guo W
AD  - Department of Ophthalmology, Ninth People's Hospital Affiliated With Shanghai 
      Jiao Tong University School of Medicine, Shanghai, China. Electronic address: 
      wyguo@163.com.
LA  - eng
PT  - Journal Article
DEP - 20170812
PL  - United States
TA  - Am J Ophthalmol
JT  - American journal of ophthalmology
JID - 0370500
RN  - Early-Onset Glaucoma
SB  - IM
CIN - Am J Ophthalmol. 2018 Feb;186:173-174. PMID: 29221824
CIN - Am J Ophthalmol. 2018 Feb;186:174. PMID: 29224687
MH  - Cohort Studies
MH  - Female
MH  - Follow-Up Studies
MH  - Glaucoma/diagnosis/physiopathology/*surgery
MH  - Humans
MH  - Infant
MH  - Intraocular Pressure/physiology
MH  - Intraoperative Complications
MH  - Male
MH  - Optic Disk/pathology
MH  - Optic Nerve Diseases/diagnosis
MH  - Postoperative Complications
MH  - Retrospective Studies
MH  - Sturge-Weber Syndrome/diagnosis/physiopathology/*surgery
MH  - Tonometry, Ocular
MH  - Trabeculectomy/*methods
MH  - Visual Acuity/physiology
EDAT- 2017/08/16 06:00
MHDA- 2017/10/04 06:00
CRDT- 2017/08/16 06:00
PHST- 2017/04/12 00:00 [received]
PHST- 2017/08/01 00:00 [revised]
PHST- 2017/08/04 00:00 [accepted]
PHST- 2017/08/16 06:00 [pubmed]
PHST- 2017/10/04 06:00 [medline]
PHST- 2017/08/16 06:00 [entrez]
AID - S0002-9394(17)30335-5 [pii]
AID - 10.1016/j.ajo.2017.08.002 [doi]
PST - ppublish
SO  - Am J Ophthalmol. 2017 Oct;182:141-146. doi: 10.1016/j.ajo.2017.08.002. Epub 2017 
      Aug 12.