PMID- 28818590 OWN - NLM STAT- MEDLINE DCOM- 20171214 LR - 20181202 IS - 1879-1298 (Electronic) IS - 0045-6535 (Linking) VI - 186 DP - 2017 Nov TI - Emerging and legacy flame retardants in indoor dust from East China. PG - 635-643 LID - S0045-6535(17)31261-4 [pii] LID - 10.1016/j.chemosphere.2017.08.038 [doi] AB - To understand human exposure to dust-associated flame retardants in the biggest metropolitan area (city of Shanghai) of East China, our study determined a suite of legacy and emerging flame retardants in dust from dwellings, cars, and university computer labs. The results exhibited a consistent dominance of organophosphate flame retardants (OPFRs) over polybrominated diphenyl ethers (PBDEs) and other alternative flame retardants (AFRs) regardless of microenvironments. In addition to OPFRs, some alternative flame retardants, such as decabromodiphenyl ethane (DBDPE), 2-ethylhexyltetrabromobenzoate (EH-TBB), bis(2-ethylhexyl)-3,4,5,6-tetrabromobenzoate (BEH-TEBP), and 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE), were also frequently detected. Among them, DBDPE exhibited concentrations comparable to those of PBDEs. Comparison with international studies indicated that concentrations of summation operatorPBDEs (0.2-12.3 mug/g dry weight or dw) and summation operatorOPFRs (3.8-165.5 mug/g dw) from Shanghai dwellings (bedroom and living room) were generally in the middle of concentration ranges reported worldwide, whereas elevated DBDPE concentrations (0.1-9.5 mug/g dw) was observed compared with most other countries or regions. OPFR compositions in house dust from this study also differed from those from many other countries. This suggested inter-regional differences in market demands on the quantities and types of flame retardants. Human intake estimation suggested elevated exposure for toddlers when compared with adults, although the daily intake estimations of individual flame retardants were generally 2-4 orders of magnitude lower than the reference doses. The findings from this preliminary study developed a baseline for future evaluation of the sources and fate of emerging flame retardants and related human exposure risks in East China. CI - Copyright (c) 2017 Elsevier Ltd. All rights reserved. FAU - Peng, Changfeng AU - Peng C AD - School of Environment, Guangzhou Key Laboratory of Environmental Exposure and Health, Guangdong Key Laboratory of Environmental Pollution and Health, Jinan University, Guangzhou 510632, China. FAU - Tan, Hongli AU - Tan H AD - School of Environment, Guangzhou Key Laboratory of Environmental Exposure and Health, Guangdong Key Laboratory of Environmental Pollution and Health, Jinan University, Guangzhou 510632, China. FAU - Guo, Ying AU - Guo Y AD - School of Environment, Guangzhou Key Laboratory of Environmental Exposure and Health, Guangdong Key Laboratory of Environmental Pollution and Health, Jinan University, Guangzhou 510632, China. Electronic address: yingguo@jnu.edu.cn. FAU - Wu, Yan AU - Wu Y AD - Cooperative Wildlife Research Laboratory and Department of Zoology, Southern Illinois University Carbondale, Carbondale, IL 62901, USA. FAU - Chen, Da AU - Chen D AD - School of Environment, Guangzhou Key Laboratory of Environmental Exposure and Health, Guangdong Key Laboratory of Environmental Pollution and Health, Jinan University, Guangzhou 510632, China. Electronic address: dachen@jnu.edu.cn. LA - eng PT - Journal Article DEP - 20170811 PL - England TA - Chemosphere JT - Chemosphere JID - 0320657 RN - 0 (2-ethylhexyltetrabromobenzoate) RN - 0 (Bromobenzenes) RN - 0 (Bromobenzoates) RN - 0 (Dust) RN - 0 (Flame Retardants) RN - 0 (Halogenated Diphenyl Ethers) RN - 0 (Organophosphates) RN - 0 (decabromodiphenyl ethane) RN - 34I00D6RNM (1,2-bis(2,4,6-tribromophenoxy)ethane) SB - IM MH - Adult MH - Air Pollution, Indoor/*analysis/statistics & numerical data MH - Bromobenzenes/analysis MH - Bromobenzoates/analysis MH - Child, Preschool MH - China MH - Cities MH - Dust/*analysis MH - Environmental Exposure/*statistics & numerical data MH - Environmental Monitoring MH - Flame Retardants/*analysis MH - Halogenated Diphenyl Ethers/analysis MH - Humans MH - Organophosphates/analysis OTO - NOTNLM OT - AFRs OT - Daily intake rate OT - Flame retardants OT - Indoor dust OT - OPFRs OT - PBDEs EDAT- 2017/08/19 06:00 MHDA- 2017/12/15 06:00 CRDT- 2017/08/19 06:00 PHST- 2017/07/02 00:00 [received] PHST- 2017/08/03 00:00 [revised] PHST- 2017/08/09 00:00 [accepted] PHST- 2017/08/19 06:00 [pubmed] PHST- 2017/12/15 06:00 [medline] PHST- 2017/08/19 06:00 [entrez] AID - S0045-6535(17)31261-4 [pii] AID - 10.1016/j.chemosphere.2017.08.038 [doi] PST - ppublish SO - Chemosphere. 2017 Nov;186:635-643. doi: 10.1016/j.chemosphere.2017.08.038. Epub 2017 Aug 11.