PMID- 28818814
OWN - NLM
STAT- MEDLINE
DCOM- 20180222
LR  - 20240109
IS  - 1873-6424 (Electronic)
IS  - 0269-7491 (Print)
IS  - 0269-7491 (Linking)
VI  - 231
IP  - Pt 1
DP  - 2017 Dec
TI  - Exposure to polybrominated diphenyl ethers and perfluoroalkyl substances in a 
      remote population of Alaska Natives.
PG  - 387-395
LID - S0269-7491(16)31094-6 [pii]
LID - 10.1016/j.envpol.2017.08.020 [doi]
AB  - BACKGROUND: Many Alaska Native communities rely on a traditional marine diet that 
      contains persistent organic pollutants (POPs). The indoor environment is also a 
      source of POPs. Polybrominated diphenyl ethers (PBDEs) and perfluoroalkyl 
      substances (PFASs) are present both in the traditional diet and the home indoor 
      environment. OBJECTIVES: We assessed exposure to PBDEs and PFASs among residents 
      of two remote Alaska Native villages on St. Lawrence Island. Ninespine 
      stickleback (Pungitious pungitious) and Alaska blackfish (Dallia pectoralis) were 
      used to detect accumulation of these compounds in the local environment. METHODS: 
      Concentrations of PBDEs and PFASs were measured in dust collected from 49 
      households on St. Lawrence Island, as well as in blood serum from 85 island 
      residents. Resident ninespine stickleback and Alaska blackfish were used as 
      sentinels to detect accumulation of PBDEs and PFASs in the food web. RESULTS: 
      Serum concentrations of perfluorononanoic acid (PFNA) and perfluoroundecanoic 
      acid (PFUnDA) were elevated, despite low concentrations of PFASs in dust samples. 
      Concentrations of PBDEs in dust and serum were similar to those from the 
      contiguous United States. Statistical associations between dust and serum 
      concentrations are apparent for a small number of PBDEs, suggesting a possible 
      route of exposure. Predominant compounds were similar between human sera and 
      stickleback; however, blackfish accumulated PFASs not found in either stickleback 
      or human sera. CONCLUSION: Household dust contributes to PBDE exposure, but not 
      PFAS exposure. Elevated concentrations of long chain PFASs in serum are likely 
      due to exposure from traditional foods. The presence of both PFASs and PBDEs in 
      sentinel fish species suggests atmospheric deposition and bioaccumulation, as 
      well as local environmental contamination.
CI  - Copyright (c) 2017. Published by Elsevier Ltd.
FAU - Byrne, Samuel
AU  - Byrne S
AD  - Department of Environmental Studies, 104 Memorial Hall, St. Lawrence University, 
      Canton, NY 13617, USA. Electronic address: sbyrne@stlawu.edu.
FAU - Seguinot-Medina, Samarys
AU  - Seguinot-Medina S
AD  - Alaska Community Action on Toxics, Anchorage, AK 99503, USA.
FAU - Miller, Pamela
AU  - Miller P
AD  - Alaska Community Action on Toxics, Anchorage, AK 99503, USA.
FAU - Waghiyi, Vi
AU  - Waghiyi V
AD  - Alaska Community Action on Toxics, Anchorage, AK 99503, USA.
FAU - von Hippel, Frank A
AU  - von Hippel FA
AD  - Department of Biological Sciences and Center for Bioengineering Innovation, 
      Northern Arizona University, Flagstaff, AZ 86011, USA.
FAU - Buck, C Loren
AU  - Buck CL
AD  - Department of Biological Sciences and Center for Bioengineering Innovation, 
      Northern Arizona University, Flagstaff, AZ 86011, USA.
FAU - Carpenter, David O
AU  - Carpenter DO
AD  - Institute for Health and the Environment, University at Albany, Albany, NY 12144, 
      USA.
LA  - eng
GR  - R01 ES019620/ES/NIEHS NIH HHS/United States
PT  - Journal Article
DEP - 20170817
PL  - England
TA  - Environ Pollut
JT  - Environmental pollution (Barking, Essex : 1987)
JID - 8804476
RN  - 0 (Dust)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Fatty Acids)
RN  - 0 (Fluorocarbons)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (perfluoroundecanoic acid)
SB  - IM
MH  - *Alaska Natives
MH  - Animals
MH  - Diet
MH  - Dust/analysis
MH  - Environmental Exposure/*analysis/statistics & numerical data
MH  - Environmental Pollutants/*blood
MH  - Fatty Acids/blood
MH  - Fluorocarbons/*blood
MH  - Food
MH  - Halogenated Diphenyl Ethers/analysis/*blood
MH  - Humans
MH  - Islands
MH  - Smegmamorpha/metabolism
PMC - PMC6945979
MID - NIHMS967862
EDAT- 2017/08/19 06:00
MHDA- 2018/02/23 06:00
PMCR- 2020/01/07
CRDT- 2017/08/19 06:00
PHST- 2016/08/31 00:00 [received]
PHST- 2017/02/04 00:00 [revised]
PHST- 2017/08/05 00:00 [accepted]
PHST- 2017/08/19 06:00 [pubmed]
PHST- 2018/02/23 06:00 [medline]
PHST- 2017/08/19 06:00 [entrez]
PHST- 2020/01/07 00:00 [pmc-release]
AID - S0269-7491(16)31094-6 [pii]
AID - 10.1016/j.envpol.2017.08.020 [doi]
PST - ppublish
SO  - Environ Pollut. 2017 Dec;231(Pt 1):387-395. doi: 10.1016/j.envpol.2017.08.020. 
      Epub 2017 Aug 17.