PMID- 28818961
OWN - NLM
STAT- MEDLINE
DCOM- 20190424
LR  - 20220330
IS  - 1475-5785 (Electronic)
IS  - 1353-8047 (Linking)
VI  - 24
IP  - 2
DP  - 2018 Apr
TI  - An analogy between socioeconomic deprivation level and loss of health from 
      adverse effects of medical treatment in England.
PG  - 142-148
LID - 10.1136/injuryprev-2016-042274 [doi]
AB  - BACKGROUND: The purpose of this study was to show whether and how levels, trends 
      and patterns obtained from estimates of premature deaths from adverse effects 
      (AEs) of medical treatment depended on the deprivation level in England over the 
      24-year period, 1990-2013. We provide a report to inform decision-making 
      strategies to reduce the burden of disease arising from AEs of medical treatment 
      in the most deprived areas of the country. METHODS: Comparative analysis was 
      driven by a single cause-of-injury category-AEs of medical treatment-from the 
      Global Burden of Disease 2013 study. We report the mean values with 95% 
      uncertainty intervals (UIs) for five socioeconomic deprivation areas of England. 
      RESULTS: In the most deprived areas of England, the death rate declined from 2.27 
      (95% UI 1.65 to 2.57) to 1.54 (1.28 to 2.08) deaths (32.16% change). The death 
      rate in the least deprived areas was 1.22 (0.88 to 1.38) in 1990; it was 1.17 
      (0.97 to 1.59) in 2013 (4.1% change). Regarding disability-adjusted life year 
      (DALY) rates, the same trend is observed. Although the gap between the most 
      deprived and least deprived populations of England narrowed with regards to 
      number of deaths, and rates of deaths and DALYs from AEs of medical treatment, 
      inequalities between marginal levels of deprivation remain. CONCLUSIONS: The 
      study suggests that a relationship between deprivation level and health loss from 
      the AEs of medical treatment across England is possible. This could then be used 
      when devising and prioritising health policies and strategies.
CI  - (c) Article author(s) (or their employer(s) unless otherwise stated in the text of 
      the article) 2018. All rights reserved. No commercial use is permitted unless 
      otherwise expressly granted.
FAU - Lunevicius, Raimundas
AU  - Lunevicius R
AD  - Emergency General Surgery and Major Trauma Centre, Aintree University Hospital 
      NHS Foundation Trust, Liverpool, UK.
AD  - School of Medicine, University of Liverpool, UK.
FAU - Haagsma, Juanita A
AU  - Haagsma JA
AD  - Institute for Health Metrics and Evaluation, University of Washington, Seattle, 
      Washington, USA.
AD  - Erasmus University Medical Center, Rotterdam, The Netherlands.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20170817
PL  - England
TA  - Inj Prev
JT  - Injury prevention : journal of the International Society for Child and Adolescent 
      Injury Prevention
JID - 9510056
SB  - IM
MH  - England/epidemiology
MH  - Female
MH  - Health Care Surveys
MH  - Health Status Disparities
MH  - Humans
MH  - Iatrogenic Disease/*epidemiology
MH  - Incidence
MH  - Male
MH  - *Poverty Areas
MH  - Quality-Adjusted Life Years
OTO - NOTNLM
OT  - DALY
OT  - England
OT  - adverse effects
OT  - mortality
OT  - population health
COIS- Competing interests: None declared.
EDAT- 2017/08/19 06:00
MHDA- 2019/04/25 06:00
CRDT- 2017/08/19 06:00
PHST- 2016/11/12 00:00 [received]
PHST- 2017/05/03 00:00 [revised]
PHST- 2017/05/05 00:00 [accepted]
PHST- 2017/08/19 06:00 [pubmed]
PHST- 2019/04/25 06:00 [medline]
PHST- 2017/08/19 06:00 [entrez]
AID - injuryprev-2016-042274 [pii]
AID - 10.1136/injuryprev-2016-042274 [doi]
PST - ppublish
SO  - Inj Prev. 2018 Apr;24(2):142-148. doi: 10.1136/injuryprev-2016-042274. Epub 2017 
      Aug 17.