PMID- 28819712 OWN - NLM STAT- MEDLINE DCOM- 20180403 LR - 20181202 IS - 1534-6293 (Electronic) IS - 1528-4042 (Linking) VI - 17 IP - 10 DP - 2017 Aug 17 TI - Optical Coherence Tomography to Differentiate Papilledema from Pseudopapilledema. PG - 74 LID - 10.1007/s11910-017-0790-6 [doi] AB - PURPOSE OF REVIEW: Mild papilledema may be difficult to distinguish by clinical observation from pseudopapilledema. An accurate diagnosis is critical to avoid invasive workup and unwarranted treatment. In this review, we focus on the development and subsequent role of optical coherence tomography (OCT) in detecting and differentiating optic nerve head drusen (ONHD) from papilledema and other causes of acquired swelling of the optic disc. RECENT FINDINGS: Newer OCT technologies which permit deeper penetration to improve detection of ONHD were also reviewed. Enhanced depth imaging (EDI) spectral-domain OCT and swept-source (SS) OCT are currently recognized as the most reliable and sensitive tools to diagnose ONHD. OCT devices currently available provide a means to quantify drusen dimensions, to evaluate the integrity of neighboring structures and to monitor axonal and neuronal damage, yielding additional information to better understand the relationship between the morphological features of drusen, and their effects on the structure and function of the optic nerve. FAU - Rebolleda, Gema AU - Rebolleda G AD - Department of Ophthalmology, Hospital Universitario Ramon y Cajal (IRYCIS), Carretera de Colmenar Viejo Km 9.100, 28034, Madrid, Spain. FAU - Kawasaki, Aki AU - Kawasaki A AD - Department of Ophthalmology, Hopital Ophtalmique Jules Gonin, University Lausanne, Lausanne, Switzerland. FAU - de Juan, Victoria AU - de Juan V AD - Department of Ophthalmology, Hospital Universitario Ramon y Cajal (IRYCIS), Carretera de Colmenar Viejo Km 9.100, 28034, Madrid, Spain. victoriadejuanryc@gmail.com. FAU - Oblanca, Noelia AU - Oblanca N AD - Department of Ophthalmology, Hospital Universitario Ramon y Cajal (IRYCIS), Carretera de Colmenar Viejo Km 9.100, 28034, Madrid, Spain. FAU - Munoz-Negrete, Francisco Jose AU - Munoz-Negrete FJ AD - Department of Ophthalmology, Hospital Universitario Ramon y Cajal (IRYCIS), Carretera de Colmenar Viejo Km 9.100, 28034, Madrid, Spain. LA - eng PT - Journal Article PT - Review DEP - 20170817 PL - United States TA - Curr Neurol Neurosci Rep JT - Current neurology and neuroscience reports JID - 100931790 RN - Pseudopapilledema SB - IM MH - Diagnosis, Differential MH - Eye Diseases, Hereditary/*diagnostic imaging/pathology MH - Humans MH - Optic Disk/diagnostic imaging/pathology MH - Optic Disk Drusen/diagnostic imaging/pathology MH - Optic Nerve/diagnostic imaging/pathology MH - Optic Nerve Diseases/*diagnostic imaging/pathology MH - Papilledema/*diagnostic imaging/pathology MH - Tomography, Optical Coherence/*methods/standards/trends OTO - NOTNLM OT - Enhanced depth imaging OT - Optic disc drusen OT - Optical coherence tomography OT - Papilledema OT - Pseudo-papilledema EDAT- 2017/08/19 06:00 MHDA- 2018/04/04 06:00 CRDT- 2017/08/19 06:00 PHST- 2017/08/19 06:00 [entrez] PHST- 2017/08/19 06:00 [pubmed] PHST- 2018/04/04 06:00 [medline] AID - 10.1007/s11910-017-0790-6 [pii] AID - 10.1007/s11910-017-0790-6 [doi] PST - epublish SO - Curr Neurol Neurosci Rep. 2017 Aug 17;17(10):74. doi: 10.1007/s11910-017-0790-6.