PMID- 28823132
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 1011-2367 (Print)
IS  - 1976-5517 (Electronic)
IS  - 1011-2367 (Linking)
VI  - 31
IP  - 2
DP  - 2018 Feb
TI  - A short-term supranutritional vitamin E supplementation alleviated respiratory 
      alkalosis but did not reduce oxidative stress in heat stressed pigs.
PG  - 263-269
LID - 10.5713/ajas.17.0256 [doi]
AB  - OBJECTIVE: Heat stress (HS) triggers oxidative stress and respiratory alkalosis 
      in pigs. The objective of this experiment was to study whether a short-term 
      supranutritional amount of dietary vitamin E (VE) can mitigate oxidative stress 
      and respiratory alkalosis in heat-stressed pigs. METHODS: A total of 24 pigs were 
      given either a control diet (17 IU/kg VE) or a high VE (200 IU/kg VE; HiVE) diet 
      for 14 d, then exposed to thermoneutral (TN; 20 degrees C, 45% humidity) or HS (35 degrees C, 35% 
      to 45% humidity, 8 h daily) conditions for 7 d. Respiration rate and rectal 
      temperature were measured three times daily during the thermal exposure. Blood 
      gas variables and oxidative stress markers were studied in blood samples 
      collected on d 7. RESULTS: Although HiVE diet did not affect the elevated rectal 
      temperature or respiration rate observed during HS, it alleviated (all p<0.05 for 
      dietxtemperature) the loss of blood CO(2) partial pressure and bicarbonate, as 
      well as the increase in blood pH in the heat-stressed pigs. The HS reduced (p = 
      0.003) plasma biological antioxidant potential (BAP) and tended to increase (p = 
      0.067) advanced oxidized protein products (AOPP) in the heat-stressed pigs, 
      suggesting HS triggers oxidative stress. The HiVE diet did not affect plasma BAP 
      or AOPP. Only under TN conditions the HiVE diet reduced the plasma reactive 
      oxygen metabolites (p<0.05 for dietx temperature). CONCLUSION: A short-term 
      supplementation with 200 IU/kg VE partially alleviated respiratory alkalosis but 
      did not reduce oxidative stress in heat-stressed pigs.
FAU - Liu, Fan
AU  - Liu F
AUID- ORCID: 0000-0003-2644-2416
AD  - Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, 
      Parkville 3010, Australia.
AD  - Rivalea Australia Pty Ltd, Corowa 2646, Australia.
FAU - Celi, Pietro
AU  - Celi P
AD  - Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, 
      Parkville 3010, Australia.
AD  - DSM Nutritional Products, Animal Nutrition and Health, Columbia, MD 21045, USA.
FAU - Chauhan, Surinder Singh
AU  - Chauhan SS
AUID- ORCID: 0000-0003-1150-379X
AD  - Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, 
      Parkville 3010, Australia.
FAU - Cottrell, Jeremy James
AU  - Cottrell JJ
AUID- ORCID: 0000-0002-1899-2090
AD  - Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, 
      Parkville 3010, Australia.
FAU - Leury, Brian Joseph
AU  - Leury BJ
AD  - Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, 
      Parkville 3010, Australia.
FAU - Dunshea, Frank Rowland
AU  - Dunshea FR
AUID- ORCID: 0000-0003-3998-1240
AD  - Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, 
      Parkville 3010, Australia.
LA  - eng
PT  - Journal Article
DEP - 20170816
PL  - Korea (South)
TA  - Asian-Australas J Anim Sci
JT  - Asian-Australasian journal of animal sciences
JID - 9884245
PMC - PMC5767509
OTO - NOTNLM
OT  - Heat Stress
OT  - Oxidative Stress
OT  - Physiology
OT  - Pigs
OT  - Respiratory Alkalosis
OT  - Vitamin E
COIS- CONFLICT OF INTEREST We certify that there is no conflict of interest with any 
      financial organization regarding the material discussed in the manuscript.
EDAT- 2017/08/22 06:00
MHDA- 2017/08/22 06:01
PMCR- 2018/02/01
CRDT- 2017/08/22 06:00
PHST- 2017/04/02 00:00 [received]
PHST- 2017/06/14 00:00 [revised]
PHST- 2017/07/29 00:00 [accepted]
PHST- 2017/08/22 06:00 [pubmed]
PHST- 2017/08/22 06:01 [medline]
PHST- 2017/08/22 06:00 [entrez]
PHST- 2018/02/01 00:00 [pmc-release]
AID - ajas.17.0256 [pii]
AID - ajas-31-2-263 [pii]
AID - 10.5713/ajas.17.0256 [doi]
PST - ppublish
SO  - Asian-Australas J Anim Sci. 2018 Feb;31(2):263-269. doi: 10.5713/ajas.17.0256. 
      Epub 2017 Aug 16.