PMID- 28828517 OWN - NLM STAT- MEDLINE DCOM- 20180827 LR - 20181202 IS - 1432-2323 (Electronic) IS - 0364-2313 (Linking) VI - 42 IP - 1 DP - 2018 Jan TI - Impact of Abdominal Wall Hernias and Repair on Patient Quality of Life. PG - 19-25 LID - 10.1007/s00268-017-4173-6 [doi] AB - BACKGROUND: The modified Activities Assessment Scale (AAS) is a 13-question abdominal wall quality of life (AW-QOL) survey validated in patients undergoing ventral hernia repair (VHR). No studies have assessed AW-QOL among individuals without abdominal wall pathology. The minimal clinically important difference (MCID) of the modified AAS and its implications for the threshold at which VHR should be offered also remain unknown. Our objectives were to (1) establish the AW-QOL of patients with a clinical abdominal wall hernia versus those with no hernia, (2) determine the MCID of the modified AAS, and (3) identify the baseline quality of life (QOL) score at which patients derive little clinical benefit from VHR. METHODS: Patient-centered outcomes data for all patients presenting to General Surgery and Hernia Clinics October-December 2016 at a single safety-net institution were collected via a prospective, cross-sectional observational study design. Primary outcome was QOL measured using the modified AAS. Secondary outcome was the MCID. RESULTS: Patients with no hernia had modified AAS scores of 81.6 (50.4-94.4), while patients with a clinically apparent hernia had lower modified AAS scores of 31.4 (12.6-58.7) (p < 0.001). The MCID threshold was 7.6 for a "slight" change and 14.9 for "definite" change. Above a modified AAS score of 81, the risk of worsening a patient's QOL by surgery is higher than the chances of improvement. CONCLUSIONS: VHR can improve 1-year postsurgical AW-QOL to levels similar to that of the general population. The MCID of the modified AAS is 7.6 points. Patients with high baseline scores should be counseled about the lack of potential benefit in QOL from elective VHR. FAU - Cherla, Deepa V AU - Cherla DV AUID- ORCID: 0000-0001-6367-8028 AD - Department of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA. deepa.cherla@uth.tmc.edu. AD - Center for Surgical Trials and Evidence-Based Practice, University of Texas Health Science Center at Houston, Houston, TX, USA. deepa.cherla@uth.tmc.edu. AD - Department of Surgery, Lyndon Baines Johnson Hospital (affiliated with the University of Texas Health Science Center at Houston), 5656 Kelley St, Houston, TX, 77026, USA. deepa.cherla@uth.tmc.edu. FAU - Moses, Maya L AU - Moses ML AD - Department of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA. FAU - Viso, Cristina P AU - Viso CP AD - Department of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA. FAU - Holihan, Julie L AU - Holihan JL AD - Department of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA. AD - Center for Surgical Trials and Evidence-Based Practice, University of Texas Health Science Center at Houston, Houston, TX, USA. FAU - Flores-Gonzalez, Juan R AU - Flores-Gonzalez JR AD - Department of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA. FAU - Kao, Lillian S AU - Kao LS AD - Department of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA. AD - Center for Surgical Trials and Evidence-Based Practice, University of Texas Health Science Center at Houston, Houston, TX, USA. FAU - Ko, Tien C AU - Ko TC AD - Department of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA. FAU - Liang, Mike K AU - Liang MK AD - Department of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA. AD - Center for Surgical Trials and Evidence-Based Practice, University of Texas Health Science Center at Houston, Houston, TX, USA. LA - eng GR - UL1 TR000371/NH/NIH HHS/United States GR - KL2 TR000370/TR/NCATS NIH HHS/United States PT - Journal Article PT - Observational Study PT - Research Support, N.I.H., Extramural PL - United States TA - World J Surg JT - World journal of surgery JID - 7704052 SB - IM MH - Abdominal Wall/surgery MH - Adult MH - Aged MH - Cross-Sectional Studies MH - Elective Surgical Procedures/rehabilitation MH - Female MH - Health Surveys MH - Hernia, Ventral/psychology/*surgery MH - Herniorrhaphy/*rehabilitation MH - Humans MH - Male MH - Middle Aged MH - Patient Outcome Assessment MH - Prospective Studies MH - Psychometrics MH - *Quality of Life EDAT- 2017/08/23 06:00 MHDA- 2018/08/28 06:00 CRDT- 2017/08/23 06:00 PHST- 2017/08/23 06:00 [pubmed] PHST- 2018/08/28 06:00 [medline] PHST- 2017/08/23 06:00 [entrez] AID - 10.1007/s00268-017-4173-6 [pii] AID - 10.1007/s00268-017-4173-6 [doi] PST - ppublish SO - World J Surg. 2018 Jan;42(1):19-25. doi: 10.1007/s00268-017-4173-6.