PMID- 28831749
OWN - NLM
STAT- MEDLINE
DCOM- 20180620
LR  - 20231105
IS  - 1538-2443 (Electronic)
IS  - 1355-0284 (Print)
IS  - 1355-0284 (Linking)
VI  - 23
IP  - 5
DP  - 2017 Oct
TI  - PML-IRIS in an HIV-2-infected patient presenting as Bell's palsy.
PG  - 789-792
LID - 10.1007/s13365-017-0565-5 [doi]
AB  - We present the case of an HIV-2-infected patient who developed progressive 
      multifocal leukoencephalopathy (PML) in the setting of immune reconstitution 
      inflammatory syndrome (IRIS) presenting as Bell's palsy. The brain MRI showed a 
      single lesion in the facial colliculus considered initially to be ischemic in 
      nature. This case report should alert clinicians that PML can occur in the 
      setting of HIV-2 infection. It also illustrates the difficulty of establishing 
      the diagnosis of PML.
FAU - Sierra Morales, Fabian
AU  - Sierra Morales F
AD  - Section of Neuro-Infectious Diseases, Rush University Medical Center, 1725 W. 
      Harrison Street, Suite 1106, Chicago, IL, 60612, USA.
AD  - Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Illingworth, Carlos
AU  - Illingworth C
AD  - Department of Neurology, Hahnemann University Hospital, Philadelphia, PA, USA.
FAU - Lin, Kathie
AU  - Lin K
AD  - Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
FAU - Rivera Agosto, Ivia
AU  - Rivera Agosto I
AD  - Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
FAU - Powell, Chloe
AU  - Powell C
AD  - Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
FAU - Sloane, Jacob A
AU  - Sloane JA
AD  - Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
FAU - Koralnik, Igor J
AU  - Koralnik IJ
AD  - Section of Neuro-Infectious Diseases, Rush University Medical Center, 1725 W. 
      Harrison Street, Suite 1106, Chicago, IL, 60612, USA. igor_koralnik@rush.edu.
AD  - Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, 
      USA. igor_koralnik@rush.edu.
LA  - eng
GR  - R01 NS047029/NS/NINDS NIH HHS/United States
GR  - R01 NS074995/NS/NINDS NIH HHS/United States
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20170822
PL  - United States
TA  - J Neurovirol
JT  - Journal of neurovirology
JID - 9508123
SB  - IM
MH  - Aged
MH  - Bell Palsy/virology
MH  - HIV Infections/*complications
MH  - *HIV-2
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/complications/virology
MH  - Leukoencephalopathy, Progressive Multifocal/*complications/pathology/virology
MH  - Male
PMC - PMC5718171
MID - NIHMS901415
OTO - NOTNLM
OT  - Bell's palsy
OT  - HIV-2
OT  - Immune reconstitution inflammatory syndrome
OT  - JC virus
OT  - Progressive multifocal leukoencephalopathy
COIS- Conflict of Interest: Fabian Sierra Morales, Carlos Illingworth, Kathie Lin, Ivia 
      Rivera Agosto, Chloe Powell, Jacob A. Sloane, and Igor J. Koralnik declare that 
      they have no conflict of interest.
EDAT- 2017/08/24 06:00
MHDA- 2018/06/21 06:00
PMCR- 2018/10/01
CRDT- 2017/08/24 06:00
PHST- 2017/06/20 00:00 [received]
PHST- 2017/07/30 00:00 [accepted]
PHST- 2017/07/24 00:00 [revised]
PHST- 2017/08/24 06:00 [pubmed]
PHST- 2018/06/21 06:00 [medline]
PHST- 2017/08/24 06:00 [entrez]
PHST- 2018/10/01 00:00 [pmc-release]
AID - 10.1007/s13365-017-0565-5 [pii]
AID - 10.1007/s13365-017-0565-5 [doi]
PST - ppublish
SO  - J Neurovirol. 2017 Oct;23(5):789-792. doi: 10.1007/s13365-017-0565-5. Epub 2017 
      Aug 22.