PMID- 28832743 OWN - NLM STAT- MEDLINE DCOM- 20170925 LR - 20170925 IS - 1678-2925 (Electronic) IS - 0004-2749 (Linking) VI - 80 IP - 3 DP - 2017 Jun TI - Effects of hemodialysis on corneal and anterior chamber morphometry and intraocular pressure in patients with end-stage renal disease. PG - 176-180 LID - S0004-27492017000300176 [pii] LID - 10.5935/0004-2749.20170043 [doi] AB - PURPOSE: To evaluate the effects of hemodialysis (HD) on corneal and anterior chamber morphometry, as well as intraocular pressure (IOP) in patients with end-stage renal disease. METHODS: Fifty right eyes were examined 30 minutes before and after HD. IOP was measured with a Goldmann applanation tonometer, and Ehlers' formula was used to calculate the corrected IOP values. The central corneal thickness (CCT), corneal volume (CV), keratometric values, anterior chamber depth (ACD), aqueous depth (AQD), anterior chamber volume (ACV), and anterior chamber angle (ACA) in the nasal and temporal quadrants were measured with a Sirius anterior segment analysis system. Blood urea nitrogen levels, body mass, and systolic and diastolic arterial pressure were also measured before and after HD. RESULTS: The mean age was 60.80 +/- 13.38 (range: 35-80) years. The mean uncorrected and corrected IOP values decreased from 18.06 +/- 3.91 and 18.31 +/- 4.83 mmHg to 16.94 +/- 3.87 and 16.95 +/- 4.74 mmHg after HD, respectively (p=0.011 and p=0.003, respectively). The mean CCT decreased from 536.38 +/- 24.73 to 533.18 +/- 27.25 microm (p=0.002), and the mean CV decreased from 57.52 +/- 3.15 to 55.68 +/- 3.55 mm(3) (p<0.001) after HD. There were no significant changes in ACD, AQD, ACV, ACA, or the keratometric values (p>0.05 for all values). There were no significant correlations between the ocular and systemic parameters (p>0.05 for all correlations). CONCLUSIONS: Uncorrected IOP, corrected IOP, CCT, and CV values decreased after HD, whereas the anterior chamber morphometry values remained similar between the measurements performed before and after HD. FAU - Caglayan, Mehtap AU - Caglayan M AD - Department of Ophthalmology, Ataturk Research and Training Hospital, Ankara, Turkey. FAU - Kosekahya, Pinar AU - Kosekahya P AD - Ulucanlar Eye Research and Training Hospital, Ankara, Turkey. FAU - Takmaz, Tamer AU - Takmaz T AD - Department of Ophthalmology, Ataturk Research and Training Hospital, Ankara, Turkey. FAU - Altunoglu, Alpaslan AU - Altunoglu A AD - Department of Nephrology, Ataturk Research and Training Hospital, Ankara, Turkey. FAU - Ayan, Berna AU - Ayan B AD - Department of Ophthalmology, Ataturk Research and Training Hospital, Ankara, Turkey. FAU - Atilgan, Cemile Ucgul AU - Atilgan CU AD - Ulucanlar Eye Research and Training Hospital, Ankara, Turkey. FAU - Uysal, Betul Seher AU - Uysal BS AD - Department of Ophthalmology, Ataturk Research and Training Hospital, Ankara, Turkey. LA - eng PT - Journal Article PL - Brazil TA - Arq Bras Oftalmol JT - Arquivos brasileiros de oftalmologia JID - 0400645 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Anterior Chamber/*pathology MH - Blood Urea Nitrogen MH - Cornea/*pathology MH - Corneal Pachymetry MH - Corneal Topography MH - Cross-Sectional Studies MH - Female MH - Humans MH - Intraocular Pressure/*physiology MH - Kidney Failure, Chronic/*physiopathology/*therapy MH - Male MH - Middle Aged MH - Reference Values MH - Renal Dialysis/*adverse effects MH - Statistics, Nonparametric MH - Time Factors MH - Tonometry, Ocular MH - Treatment Outcome EDAT- 2017/08/24 06:00 MHDA- 2017/09/26 06:00 CRDT- 2017/08/24 06:00 PHST- 2016/08/23 00:00 [received] PHST- 2017/01/16 00:00 [accepted] PHST- 2017/08/24 06:00 [entrez] PHST- 2017/08/24 06:00 [pubmed] PHST- 2017/09/26 06:00 [medline] AID - S0004-27492017000300176 [pii] AID - 10.5935/0004-2749.20170043 [doi] PST - ppublish SO - Arq Bras Oftalmol. 2017 Jun;80(3):176-180. doi: 10.5935/0004-2749.20170043.