PMID- 28840030 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200929 IS - 2072-1439 (Print) IS - 2077-6624 (Electronic) IS - 2072-1439 (Linking) VI - 9 IP - 7 DP - 2017 Jul TI - Veno-arterial extracorporeal membrane oxygenation without therapeutic anticoagulation for intra-operative cardiopulmonary support during lung transplantation. PG - E629-E631 LID - 10.21037/jtd.2017.06.11 [doi] AB - Cardiopulmonary support is frequently required during lung transplantation. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been recently shown to be an acceptable and, perhaps, safer alternative to cardiopulmonary bypass machine (CBM) for lung transplantation. However, therapeutic anticoagulation used during both these techniques can cause significant bleeding diathesis, especially in the setting of re-transplantation or when severe adhesions are encountered. Technological advances have reduced the thrombogenic potential of VA-ECMO circuits and unlike CBM, VA-ECMO does not include a reservoir containing a stagnant column of blood. Here, we demonstrate that VA-ECMO can be used without therapeutic anticoagulation for short-term intraoperative support. FAU - Bharat, Ankit AU - Bharat A AD - Division of Thoracic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - DeCamp, Malcolm M AU - DeCamp MM AD - Division of Thoracic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. LA - eng GR - K08 HL125940/HL/NHLBI NIH HHS/United States PT - Case Reports PL - China TA - J Thorac Dis JT - Journal of thoracic disease JID - 101533916 PMC - PMC5542924 OTO - NOTNLM OT - Anticoagulation OT - Lung transplantation OT - extracorporeal membrane oxygenation (ECMO) OT - heparin COIS- Conflicts of Interest: The authors have no conflicts of interest to declare. EDAT- 2017/08/26 06:00 MHDA- 2017/08/26 06:01 PMCR- 2017/07/01 CRDT- 2017/08/26 06:00 PHST- 2017/08/26 06:00 [entrez] PHST- 2017/08/26 06:00 [pubmed] PHST- 2017/08/26 06:01 [medline] PHST- 2017/07/01 00:00 [pmc-release] AID - jtd-09-07-E629 [pii] AID - 10.21037/jtd.2017.06.11 [doi] PST - ppublish SO - J Thorac Dis. 2017 Jul;9(7):E629-E631. doi: 10.21037/jtd.2017.06.11.