PMID- 28843172
OWN - NLM
STAT- MEDLINE
DCOM- 20180426
LR  - 20220331
IS  - 1872-6976 (Electronic)
IS  - 0167-4943 (Linking)
VI  - 73
DP  - 2017 Nov
TI  - Cognitive interventions in patients with dementia living in long-term care 
      facilities: Systematic review and meta-analysis.
PG  - 204-221
LID - S0167-4943(17)30035-3 [pii]
LID - 10.1016/j.archger.2017.07.017 [doi]
AB  - BACKGROUND: Previous reviews and meta-analyses demonstrated effects of cognitive 
      interventions in dementia, but none specifically considered residents with 
      dementia in long-term care (LTC) facilities. OBJECTIVE: To analyse the efficacy 
      of cognitive interventions in institutionalised individuals with dementia. 
      METHODS: After identifying 27 articles, a systematic review was performed. A 
      meta-analysis was calculated for 15 studies of the randomized controlled trials 
      regarding effects on relevant outcomes. Fixed-effects meta-analyses were 
      conducted using standardized mean differences (SMD) of changes from baseline 
      pooled using the inverse variance method. RESULTS: When comparing cognitive 
      interventions to passive control groups, the meta-analysis revealed significant 
      moderate effects on global cognition (SMD=0.47, 95% CI 0.27-0.67), 
      autobiographical memory (0.67, 0.02-1.31), and behavioral and psychological 
      symptoms in dementia (BPSD; 0.71, 0.06-1.36). Significant small effects were 
      detected for quality of life (QoL; 0.37, 0.05-0.70). Moderate effects on 
      activities of daily living (0.28; -0.02 to 0.58) failed to reach significance; no 
      effects were found on depression (0.22; -0.08 to 0.51). Significant moderate 
      effects of global cognition (0.55; 0.22-0.89) and depression (0.64; 0.21-1.07) 
      were also found for cognitive interventions contrasting active control groups. No 
      harmful events related to the participation in the interventions were observed. 
      CONCLUSION: Cognitive interventions are safe and effective for residents with 
      dementia in LTC. However, while it seems clear that cognitive benefits can 
      specifially be assigned to these forms of intervention, further research is 
      necessary to clarify whether the effects on BPSD and QoL reflect unspecific 
      changes due to additional attention. Furthermore, future studies will have to 
      determine which intervention type yields the largest benefits.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Folkerts, Ann-Kristin
AU  - Folkerts AK
AD  - Medical Psychology | Neuropsychology and Gender Studies & Center for 
      Neuropsychological Diagnostics and Intervention (CeNDI), University Hospital 
      Cologne, Kerpenerstrasse 62, 50937 Cologne, Germany.
FAU - Roheger, Mandy
AU  - Roheger M
AD  - Medical Psychology | Neuropsychology and Gender Studies & Center for 
      Neuropsychological Diagnostics and Intervention (CeNDI), University Hospital 
      Cologne, Kerpenerstrasse 62, 50937 Cologne, Germany.
FAU - Franklin, Jeremy
AU  - Franklin J
AD  - Institute of Medical Statistics, Informatics and Epidemiology (IMSIE), University 
      of Cologne, Albertus-Magnus-Platz, 50923 Cologne, Germany.
FAU - Middelstadt, Jennifer
AU  - Middelstadt J
AD  - Institute of Gerontology, University of Vechta, Driverstrasse 22, 49377 Vechta, 
      Germany.
FAU - Kalbe, Elke
AU  - Kalbe E
AD  - Medical Psychology | Neuropsychology and Gender Studies & Center for 
      Neuropsychological Diagnostics and Intervention (CeNDI), University Hospital 
      Cologne, Kerpenerstrasse 62, 50937 Cologne, Germany. Electronic address: 
      elke.kalbe@uk-koeln.de.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20170729
PL  - Netherlands
TA  - Arch Gerontol Geriatr
JT  - Archives of gerontology and geriatrics
JID - 8214379
SB  - IM
MH  - Activities of Daily Living
MH  - *Cognitive Behavioral Therapy
MH  - Dementia/psychology/*therapy
MH  - Humans
MH  - *Long-Term Care
MH  - Quality of Life
OTO - NOTNLM
OT  - Alzheimer disease
OT  - Cognition
OT  - Dementia
OT  - Meta-analysis
OT  - Nursing homes
OT  - Therapy
EDAT- 2017/08/27 06:00
MHDA- 2018/04/27 06:00
CRDT- 2017/08/27 06:00
PHST- 2017/01/11 00:00 [received]
PHST- 2017/07/03 00:00 [revised]
PHST- 2017/07/21 00:00 [accepted]
PHST- 2017/08/27 06:00 [pubmed]
PHST- 2018/04/27 06:00 [medline]
PHST- 2017/08/27 06:00 [entrez]
AID - S0167-4943(17)30035-3 [pii]
AID - 10.1016/j.archger.2017.07.017 [doi]
PST - ppublish
SO  - Arch Gerontol Geriatr. 2017 Nov;73:204-221. doi: 10.1016/j.archger.2017.07.017. 
      Epub 2017 Jul 29.