PMID- 28851194 OWN - NLM STAT- MEDLINE DCOM- 20190617 LR - 20190617 IS - 0412-4081 (Print) IS - 0412-4081 (Linking) VI - 53 IP - 8 DP - 2017 Aug 11 TI - [Pay attention to the application of the international intraocular retinoblastoma classification and sequential multiple modality treatment]. PG - 561-565 LID - 10.3760/cma.j.issn.0412-4081.2017.08.001 [doi] AB - Retinoblastoma (RB) is the most common intraocular malignancy in childhood. It may seriously affect vision, and even threaten the life. The early diagnosis rate of RB in China remains low, and the majority of patients are at late phase with high rates of enucleation and mortality. The International Intraocular Retinoblastoma Classification and TNM staging system are guidances for therapeutic choices and bases for prognosis evaluation. Based on the sequential multi-method treatment modality, chemotherapy combined with local therapy is the mainstream in dealing with RB, which may maximize the results of eye saving and even vision retaining. New therapeutic techniques including supra-selective ophthalmic artery interventional chemotherapy and intravitreal chemotherapy can further improve the efficacy of treatment, especially the eye salvage rate. The overall level of RB treatment should be improved by promoting the international staging, new therapeutic techniques, and the sequential multiple modality treatment. (Chin J Ophthalmol, 2017, 53: 561-565). FAU - Fan, X Q AU - Fan XQ AD - Department of Opthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. LA - chi PT - Journal Article PL - China TA - Zhonghua Yan Ke Za Zhi JT - [Zhonghua yan ke za zhi] Chinese journal of ophthalmology JID - 16210540R SB - IM MH - Antineoplastic Combined Chemotherapy Protocols MH - Child MH - China MH - Combined Modality Therapy MH - Eye Enucleation MH - Humans MH - Infant MH - *Retinal Neoplasms/diagnosis/therapy MH - *Retinoblastoma/diagnosis/therapy MH - Retrospective Studies OTO - NOTNLM OT - Antineoplastic protocols OT - Combined modality therapy OT - Infusions, intra-arterial OT - International classification of diseases OT - Intravitreal injections OT - Neoplasm staging OT - Retinoblastoma EDAT- 2017/08/31 06:00 MHDA- 2019/06/18 06:00 CRDT- 2017/08/31 06:00 PHST- 2017/08/31 06:00 [entrez] PHST- 2017/08/31 06:00 [pubmed] PHST- 2019/06/18 06:00 [medline] AID - 10.3760/cma.j.issn.0412-4081.2017.08.001 [doi] PST - ppublish SO - Zhonghua Yan Ke Za Zhi. 2017 Aug 11;53(8):561-565. doi: 10.3760/cma.j.issn.0412-4081.2017.08.001.