PMID- 28853429
OWN - NLM
STAT- MEDLINE
DCOM- 20180807
LR  - 20181023
IS  - 0025-7818 (Print)
IS  - 0025-7818 (Linking)
VI  - 108
IP  - 4
DP  - 2017 Aug 28
TI  - [Obstructive sleep apnea (OSA) and driving safety].
PG  - 297-303
LID - 10.23749/mdl.v108i4.6410 [doi]
AB  - Intermittent hypoxia and sleep fragmentation cause excessive daytime sleepiness 
      (EDS) and cognitive impairment in obstructive sleep apnoea (OSA); neuroimaging 
      and neurophysiological studies in patients with OSA have delineated a putative 
      regional "fingerprint" of OSA-induced brain injury: a disconnection of the 
      fronto-parietal regions and a disruption of the thalamocortical oscillator, with 
      involvement of the hippocampal formation with impaired attention, awareness, 
      working memory, time reaction, visuoconstructive and executive functions. For 
      these reasons OSA is the main medical cause of EDS and is also associated with an 
      increased risk of motor vehicle accidents (MVAs). About 7% of MVAs for a 
      population of male drivers involved in MVAs are attributable to OSA. Subjects 
      with OSA have nearly twofold increased odds of work accidents. Professional 
      drivers add fatigue to sleep deprivation. A higher risk of MVAs cannot be 
      adequately explained by OSA and sleep deprivation (SD), and EDS is a further, 
      independent risk factor like the other two. There is an association between the 
      amount of hours of sleep per night and MVA or near miss accidents (NMA) rates 
      with an inverse linear correlation. When OSA, SD or EDS are present, the risk of 
      MVAs or NMAs in truck drivers is severely increased. Taking a rest break or a nap 
      appear to be protective against MVAs e NMAs and they should be considered a 
      primary prevention strategy together with screening for OSA, EDS, and SD.
FAU - Garbarino, Sergio
AU  - Garbarino S
AD  - . sgarbarino.neuro@gmail.com.
LA  - ita
PT  - Journal Article
TT  - Apnee ostruttive nel soono (OSA) e Sicurezza alla Guida.
DEP - 20170828
PL  - Italy
TA  - Med Lav
JT  - La Medicina del lavoro
JID - 0401176
SB  - IM
MH  - Automobile Driving/*standards
MH  - Disorders of Excessive Somnolence/etiology
MH  - Humans
MH  - Safety
MH  - *Sleep Apnea, Obstructive/complications
OTO - NOTNLM
OT  - OSA
OT  - deficit neurocognitivi
OT  - incidenti stradali
OT  - sicurezza
OT  - sonnolenza diurna
EDAT- 2017/08/31 06:00
MHDA- 2018/08/08 06:00
CRDT- 2017/08/31 06:00
PHST- 2017/04/26 00:00 [received]
PHST- 2017/07/18 00:00 [accepted]
PHST- 2017/08/31 06:00 [entrez]
PHST- 2017/08/31 06:00 [pubmed]
PHST- 2018/08/08 06:00 [medline]
AID - 10.23749/mdl.v108i4.6410 [doi]
PST - epublish
SO  - Med Lav. 2017 Aug 28;108(4):297-303. doi: 10.23749/mdl.v108i4.6410.