PMID- 28855658
OWN - NLM
STAT- MEDLINE
DCOM- 20190423
LR  - 20231112
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 7
IP  - 1
DP  - 2017 Aug 30
TI  - The Diagnostic Value of Global Longitudinal Strain (GLS) on Myocardial Infarction 
      Size by Echocardiography: A Systematic Review and Meta-analysis.
PG  - 10082
LID - 10.1038/s41598-017-09096-2 [doi]
LID - 10082
AB  - A systematic review and meta-analysis of prospective randomized studies were 
      performed to evaluate the diagnostic value of measuring global longitudinal 
      strain (GLS) using speckle tracking echocardiography (STE) in determining 
      myocardial infarction (MI) size, which is usually measured based on late 
      gadolinium enhancement (LGE) by cardiovascular magnetic resonance (CMR). Eleven 
      trials with a total of 765 patients were included. The pooled correlation was 
      0.70 (95% CI: 0.64, 0.74) between two-dimensional (2D) GLS and the LGE 
      percentage, and it was 0.55 (95% CI: 0.19, 0.78) for three-dimensional (3D) GLS. 
      Pooled diagnostic estimates for 2D GLS to differentiate an MI size >12% were as 
      follows: sensitivity, 0.77 (95% CI: 0.61, 0.90); specificity, 0.86 (95% CI: 0.68, 
      0.96); positive likelihood ratio (PLR), 8.13 (95% CI: 1.90, 26.61); negative 
      likelihood ratio (NLR), 0.28 (95% CI: 0.10, 0.54); and diagnostic odds ratio 
      (DOR), 39.87 (95% CI: 4.12, 172.83). The estimated area under the curve (AUC) of 
      the summary receiver operating characteristic (SROC) curve was 0.702. The 2D STE 
      results positively correlated with the infarction size quantified by CMR for 
      patients who had experienced their first MI. This approach can serve as a good 
      diagnostic index for assessing infarction area. However, more consolidated STE 
      studies are still needed to determine the value of 3D STE.
FAU - Diao, Kai-Yue
AU  - Diao KY
AD  - Department of Radiology, State Key Laboratory of Biotherapy, West China Hospital, 
      Sichuan University, Chengdu, China.
FAU - Yang, Zhi-Gang
AU  - Yang ZG
AD  - Department of Radiology, State Key Laboratory of Biotherapy, West China Hospital, 
      Sichuan University, Chengdu, China. yangzg666@163.com.
FAU - Ma, Min
AU  - Ma M
AD  - Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 
      China.
AD  - Department of Cardiology, The Sixth People's Hospital of Chengdu, Chengdu, China.
FAU - He, Yong
AU  - He Y
AD  - Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 
      China.
FAU - Zhao, Qin
AU  - Zhao Q
AD  - Department of Radiology, State Key Laboratory of Biotherapy, West China Hospital, 
      Sichuan University, Chengdu, China.
FAU - Liu, Xi
AU  - Liu X
AD  - Department of Radiology, State Key Laboratory of Biotherapy, West China Hospital, 
      Sichuan University, Chengdu, China.
FAU - Gao, Yue
AU  - Gao Y
AD  - Department of Radiology, State Key Laboratory of Biotherapy, West China Hospital, 
      Sichuan University, Chengdu, China.
FAU - Xie, Lin-Jun
AU  - Xie LJ
AD  - Department of Radiology, Key Laboratory of Birth Defects and Related Diseases of 
      Women and Children of Ministry of Education, West China Second University 
      Hospital, Sichuan University, Chengdu, China.
FAU - Guo, Ying-Kun
AU  - Guo YK
AD  - Department of Radiology, Key Laboratory of Birth Defects and Related Diseases of 
      Women and Children of Ministry of Education, West China Second University 
      Hospital, Sichuan University, Chengdu, China. gykpanda@163.com.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Systematic Review
DEP - 20170830
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Aged
MH  - Area Under Curve
MH  - Contrast Media/metabolism
MH  - Echocardiography/*methods
MH  - Female
MH  - Gadolinium/metabolism
MH  - Humans
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnostic imaging/metabolism/pathology
MH  - Myocardium/pathology
MH  - Odds Ratio
MH  - Prospective Studies
MH  - Randomized Controlled Trials as Topic
MH  - Sensitivity and Specificity
PMC - PMC5577208
COIS- The authors declare that they have no competing interests.
EDAT- 2017/09/01 06:00
MHDA- 2019/04/24 06:00
PMCR- 2017/08/30
CRDT- 2017/09/01 06:00
PHST- 2017/04/21 00:00 [received]
PHST- 2017/07/20 00:00 [accepted]
PHST- 2017/09/01 06:00 [entrez]
PHST- 2017/09/01 06:00 [pubmed]
PHST- 2019/04/24 06:00 [medline]
PHST- 2017/08/30 00:00 [pmc-release]
AID - 10.1038/s41598-017-09096-2 [pii]
AID - 9096 [pii]
AID - 10.1038/s41598-017-09096-2 [doi]
PST - epublish
SO  - Sci Rep. 2017 Aug 30;7(1):10082. doi: 10.1038/s41598-017-09096-2.