PMID- 28862781
OWN - NLM
STAT- MEDLINE
DCOM- 20180712
LR  - 20230816
IS  - 1365-2826 (Electronic)
IS  - 0953-8194 (Linking)
VI  - 29
IP  - 11
DP  - 2017 Nov
TI  - Effects of lateral olfactory tract stimulation on Fos immunoreactivity in 
      vasopressin neurones of the rat piriform cortex.
LID - 10.1111/jne.12531 [doi]
AB  - In the main olfactory system, odours are registered at the main olfactory 
      epithelium and are then processed at the main olfactory bulb (MOB) and, 
      subsequently, by the anterior olfactory nucleus (AON), the piriform cortex (PC) 
      and the cortical amygdala. Previously, we reported populations of vasopressin 
      neurones in different areas of the rat olfactory system, including the MOB, 
      accessory olfactory bulb (AOB) and the AON and showed that these are involved in 
      the coding of social odour information. Utilising immunohistochemistry and a 
      transgenic rat in which an enhanced green fluorescent protein reporter gene is 
      expressed in vasopressin neurones (eGFP-vasopressin), we now show a population of 
      vasopressin neurones in the PC. The vasopressin neurones are predominantly 
      located in the layer II of the PC and the majority co-express the excitatory 
      transmitter glutamate. Furthermore, there is no sex difference in the number of 
      neurones expressing vasopressin. Electrical stimulation of the lateral olfactory 
      tract leads to a significant increase in the number of Fos-positive nuclei in the 
      PC, MOB, AOB, dorsal AON and supraoptic nucleus (SON). However, there was only a 
      significant increase in Fos expression in vasopressin cells of the PC and SON. 
      Thus, functionally distinct populations of vasopressin cells are implicated in 
      olfactory processing at multiple stages of the olfactory pathway.
CI  - (c) 2017 British Society for Neuroendocrinology.
FAU - Tsuji, C
AU  - Tsuji C
AD  - Centre for Integrative Physiology, University of Edinburgh, Edinburgh, UK.
FAU - Tsuji, T
AU  - Tsuji T
AD  - Centre for Integrative Physiology, University of Edinburgh, Edinburgh, UK.
FAU - Allchorne, A
AU  - Allchorne A
AD  - Centre for Integrative Physiology, University of Edinburgh, Edinburgh, UK.
FAU - Leng, G
AU  - Leng G
AD  - Centre for Integrative Physiology, University of Edinburgh, Edinburgh, UK.
FAU - Ludwig, M
AU  - Ludwig M
AUID- ORCID: 0000-0001-9983-4950
AD  - Centre for Integrative Physiology, University of Edinburgh, Edinburgh, UK.
LA  - eng
GR  - MR/M022838/1/MRC_/Medical Research Council/United Kingdom
GR  - BB/J004723/1/BB_/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Neuroendocrinol
JT  - Journal of neuroendocrinology
JID - 8913461
RN  - 0 (Proto-Oncogene Proteins c-fos)
RN  - 11000-17-2 (Vasopressins)
RN  - 3KX376GY7L (Glutamic Acid)
SB  - IM
MH  - Animals
MH  - Cell Count
MH  - Electric Stimulation
MH  - Female
MH  - Glutamic Acid/metabolism
MH  - Male
MH  - Neurons/*metabolism
MH  - Olfactory Bulb/*physiology
MH  - Olfactory Pathways/*physiology
MH  - Olfactory Perception/physiology
MH  - Piriform Cortex/*cytology/physiology
MH  - Proto-Oncogene Proteins c-fos/*immunology/*metabolism
MH  - Rats
MH  - Rats, Transgenic
MH  - Sex Characteristics
MH  - Supraoptic Nucleus/physiology
MH  - Vasopressins/*metabolism
OTO - NOTNLM
OT  - accessory olfactory bulb
OT  - anterior olfactory nucleus
OT  - main olfactory bulb
OT  - supraoptic nucleus
EDAT- 2017/09/02 06:00
MHDA- 2018/07/13 06:00
CRDT- 2017/09/02 06:00
PHST- 2017/07/14 00:00 [received]
PHST- 2017/08/22 00:00 [revised]
PHST- 2017/08/28 00:00 [accepted]
PHST- 2017/09/02 06:00 [pubmed]
PHST- 2018/07/13 06:00 [medline]
PHST- 2017/09/02 06:00 [entrez]
AID - 10.1111/jne.12531 [doi]
PST - ppublish
SO  - J Neuroendocrinol. 2017 Nov;29(11). doi: 10.1111/jne.12531.