PMID- 28863074
OWN - NLM
STAT- MEDLINE
DCOM- 20180326
LR  - 20180326
IS  - 1530-0315 (Electronic)
IS  - 0195-9131 (Linking)
VI  - 50
IP  - 1
DP  - 2018 Jan
TI  - Interval Walking Training and Nutritional Intake to Increase Plasma Volume in 
      Elderly.
PG  - 151-158
LID - 10.1249/MSS.0000000000001416 [doi]
AB  - PURPOSE: Aerobic training-induced plasma volume (PV) expansion improves 
      thermoregulation, and carbohydrate (CHO) + whey protein supplementation enhanced 
      the effects in older people; however, these were suggested by studies on 
      gym-based cycling training but not on home-based interval walking training (IWT). 
      Moreover, long-term walking training effects on PV remain unknown. METHODS: 
      Seventeen male and 10 female subjects (~69 yr), having performed IWT for >/=24 
      months before the study, were used. After pre-intervention measurement (PRE) of 
      PV, plasma albumin content (Albcont), fasting glucose concentration ([Glc]f), and 
      HbA1c, the subjects were randomly divided into two groups: CHO and Pro-CHO, 
      either consuming CHO (22.5 g) alone or CHO (15 g) + whey protein (10 g), 
      respectively, during additional 5-month IWT from May to November, 2009. After the 
      additional IWT, we measured the same variables again (postintervention 
      measurement). RESULTS: The baseline PV and Albcont were significantly correlated 
      with the number of IWT days for the 12 months preceding PRE (r = 0.716, P < 0.001 
      and r = 0.671, P < 0.001, respectively). In postintervention, PV and Albcont 
      marginally decreased in CHO from the baselines (P = 0.081 and P = 0.130, 
      respectively) with increased HbA1c (P < 0.001) after correction for the baseline 
      [Glc]f by ANCOVA, but these values remained unchanged in Pro-CHO (both, P > 
      0.74), with significant differences in the changes between groups (P = 0.020, P = 
      0.041, and P = 0.018 respectively). CONCLUSIONS: PV was proportional to the 
      number of IWT days for 12 months and a CHO + whey protein supplementation during 
      the 5-month IWT prevented PV reduction for the period of no supplementation, 
      which might be partially linked with blood glucose control mechanisms.
FAU - Uchida, Koji
AU  - Uchida K
AD  - 1Department of Sports Medical Sciences, Shinshu University Graduate School of 
      Medicine and Institute for Biomedical Sciences, JAPAN; and 2Saga Nutraceutical 
      Research Institute, Otsuka Pharmaceutical CO., Ltd., Higashisefuri, Kanzaki, 
      JAPAN.
FAU - Kamijo, Yoshi-Ichiro
AU  - Kamijo YI
FAU - Ikegawa, Shigeki
AU  - Ikegawa S
FAU - Hamada, Koichiro
AU  - Hamada K
FAU - Masuki, Shizue
AU  - Masuki S
FAU - Nose, Hiroshi
AU  - Nose H
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
SB  - IM
MH  - Aged
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Dietary Proteins/*administration & dosage
MH  - *Dietary Supplements
MH  - Female
MH  - Humans
MH  - Male
MH  - Oxygen Consumption
MH  - *Plasma Volume
MH  - Walking/*physiology
EDAT- 2017/09/02 06:00
MHDA- 2018/03/27 06:00
CRDT- 2017/09/02 06:00
PHST- 2017/09/02 06:00 [pubmed]
PHST- 2018/03/27 06:00 [medline]
PHST- 2017/09/02 06:00 [entrez]
AID - 10.1249/MSS.0000000000001416 [doi]
PST - ppublish
SO  - Med Sci Sports Exerc. 2018 Jan;50(1):151-158. doi: 10.1249/MSS.0000000000001416.