PMID- 28863873 OWN - NLM STAT- MEDLINE DCOM- 20181016 LR - 20181016 IS - 0929-6646 (Print) IS - 0929-6646 (Linking) VI - 117 IP - 7 DP - 2018 Jul TI - Evaluation of the associations between immunoglobulin E levels and the number of natural teeth. PG - 605-612 LID - S0929-6646(17)30174-2 [pii] LID - 10.1016/j.jfma.2017.08.001 [doi] AB - BACKGROUND/PURPOSE: The purpose of the study was to evaluate the association between the number of natural teeth and the total serum immunoglobulin E (IgE), allergen-specific IgE against Dermatophagoides farina, allergen-specific IgE against cockroaches, or allergen-specific IgE against dogs with nationally representative data using the Korean National Health and Nutrition Examination Survey (KNHANES). METHODS: This study involved a cross-sectional analysis using KNHANES data from 2010. A total of 1916 participants were eligible for this study. Multiple regression analyses were used to evaluate the risk of tooth loss in relation to IgE levels. The model was adjusted for age, sex, body mass index, smoking habits, drinking habits, exercise habits, vitamin D levels, metabolic syndrome, allergic rhinitis, asthma, atopic dermatitis, and tooth-brushing frequency. RESULTS: The number of natural teeth of the first quartile to the fourth quartile of total serum IgE were 25.9 +/- 0.2, 25.9 +/- 0.2, 25.1 +/- 0.2, and 25.4 +/- 0.2, respectively, showing an inverse association (P < 0.05). The number of natural teeth of the first quartile to the fourth quartile of allergen-specific IgE against Dermatophagoides farina and allergen-specific IgE against dogs farina both showed an inverse association with statistical significance (P < 0.05). CONCLUSION: This study clearly showed the inverse association between total serum IgE and number of natural teeth after adjustments, especially regarding participants without systemic diseases, including diabetes mellitus, hypertension, metabolic diseases, and obesity. CI - Copyright (c) 2017. Published by Elsevier B.V. FAU - Han, Kyungdo AU - Han K AD - Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. FAU - Lee, Eunjoo AU - Lee E AD - Big Data Steering Department, National Health Insurance Service, Wonju, Republic of Korea. FAU - Park, Jun-Beom AU - Park JB AD - Department of Periodontics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: jbassoonis@yahoo.co.kr. LA - eng PT - Journal Article DEP - 20170831 PL - Singapore TA - J Formos Med Assoc JT - Journal of the Formosan Medical Association = Taiwan yi zhi JID - 9214933 RN - 0 (Allergens) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adult MH - Aged MH - Allergens/immunology MH - Animals MH - Body Mass Index MH - Cockroaches MH - Cross-Sectional Studies MH - *Dentition, Permanent MH - Dermatophagoides farinae MH - Diabetes Mellitus/blood MH - Dogs MH - Female MH - Humans MH - Hypertension/blood MH - Immunoglobulin E/*blood MH - Male MH - Metabolic Syndrome/blood MH - Middle Aged MH - Nutrition Surveys MH - Regression Analysis MH - Republic of Korea MH - Tooth Loss/*blood MH - Waist Circumference OTO - NOTNLM OT - Allergy and immunology OT - Epidemiology OT - Health surveys OT - Immunoglobulin E OT - Natural teeth OT - Oral health EDAT- 2017/09/03 06:00 MHDA- 2018/10/17 06:00 CRDT- 2017/09/03 06:00 PHST- 2017/03/04 00:00 [received] PHST- 2017/05/26 00:00 [revised] PHST- 2017/08/02 00:00 [accepted] PHST- 2017/09/03 06:00 [pubmed] PHST- 2018/10/17 06:00 [medline] PHST- 2017/09/03 06:00 [entrez] AID - S0929-6646(17)30174-2 [pii] AID - 10.1016/j.jfma.2017.08.001 [doi] PST - ppublish SO - J Formos Med Assoc. 2018 Jul;117(7):605-612. doi: 10.1016/j.jfma.2017.08.001. Epub 2017 Aug 31.