PMID- 28870490 OWN - NLM STAT- MEDLINE DCOM- 20180731 LR - 20180801 IS - 1873-1708 (Electronic) IS - 0890-6238 (Linking) VI - 74 DP - 2017 Dec TI - A study to support regulatory submission assessing effects of Tri(2-ethylhexyl) trimellitate (TEHTM) upon pre and post-natal development in the rat, with a comparative group receiving Di(2-ethyl hexyl) phthalate (DEHP) included. PG - 59-69 LID - S0890-6238(16)30368-9 [pii] LID - 10.1016/j.reprotox.2017.08.020 [doi] AB - Oral exposure of rodents to the plasticizer, Di(2-ethyl hexyl) phthalate (DEHP), elicits birth defects and effects upon the reproductive tract. There is currently limited published information regarding potential developmental effects in rodents of another phthalate ester, TEHTM. CI - Crown Copyright (c) 2017. Published by Elsevier Inc. All rights reserved. FAU - Renaut, Steven D AU - Renaut SD AD - Envigo, Eye, Suffolk, IP23 7PX, UK. Electronic address: steve.renaut@envigo.com. FAU - Whiteley, Michele AU - Whiteley M AD - Flint Hills Resources, LP, Wichita, KS, 67220, USA. LA - eng PT - Journal Article DEP - 20170921 PL - United States TA - Reprod Toxicol JT - Reproductive toxicology (Elmsford, N.Y.) JID - 8803591 RN - 0 (Benzoates) RN - 0 (Plasticizers) RN - 0 (Teratogens) RN - 3319-31-1 (tri-(2-ethylhexyl)trimellitate) RN - C42K0PH13C (Diethylhexyl Phthalate) SB - IM MH - Animals MH - Benzoates/*toxicity MH - Diethylhexyl Phthalate/*toxicity MH - Embryonic Development/drug effects MH - Female MH - Fetal Development/drug effects MH - Lactation MH - Male MH - Maternal-Fetal Exchange MH - Plasticizers/*toxicity MH - Pregnancy MH - Rats MH - Rats, Sprague-Dawley MH - Sexual Maturation/drug effects MH - Teratogens/*toxicity OTO - NOTNLM OT - Male reproductive tract toxicity OT - Phthalate OT - Regulatory toxicology OT - Reproductive toxicity OT - Reproductive toxicology EDAT- 2017/09/06 06:00 MHDA- 2018/08/01 06:00 CRDT- 2017/09/06 06:00 PHST- 2016/10/27 00:00 [received] PHST- 2017/08/14 00:00 [revised] PHST- 2017/08/29 00:00 [accepted] PHST- 2017/09/06 06:00 [pubmed] PHST- 2018/08/01 06:00 [medline] PHST- 2017/09/06 06:00 [entrez] AID - S0890-6238(16)30368-9 [pii] AID - 10.1016/j.reprotox.2017.08.020 [doi] PST - ppublish SO - Reprod Toxicol. 2017 Dec;74:59-69. doi: 10.1016/j.reprotox.2017.08.020. Epub 2017 Sep 21.