PMID- 28870554
OWN - NLM
STAT- MEDLINE
DCOM- 20180508
LR  - 20220317
IS  - 1878-5883 (Electronic)
IS  - 0022-510X (Linking)
VI  - 380
DP  - 2017 Sep 15
TI  - Effectiveness of speech language therapy either alone or with add-on 
      computer-based language therapy software (Malayalam version) for early post 
      stroke aphasia: A feasibility study.
PG  - 137-141
LID - S0022-510X(17)30444-6 [pii]
LID - 10.1016/j.jns.2017.07.010 [doi]
AB  - CONTEXT AND AIMS: This study aimed to assess the feasibility of professional 
      based conventional speech language therapy (SLT) either alone (Group A/less 
      intensive) or assisted by novel computer based local language software (Group 
      B/more intensive) for rehabilitation in early post stroke aphasia. SETTINGS AND 
      DESIGN: Comprehensive Stroke Care Center of a tertiary health care institute 
      situated in South India, with the study design being prospective open randomised 
      controlled trial with blinded endpoint evaluation. MATERIAL AND METHODS: This 
      study recruited 24 right handed first ever acute ischemic stroke patients above 
      15years of age affecting middle cerebral artery territory within 90days of stroke 
      onset with baseline Western Aphasia Battery (WAB) Aphasia Quotient (AQ) score of 
      <93.8 between September 2013 and January 2016.The recruited subjects were block 
      randomised into either Group A/less intensive or Group B/more intensive therapy 
      arms, in order to receive 12 therapy sessions of conventional professional based 
      SLT of 1h each in both groups, with an additional 12h of computer based language 
      therapy in Group B over 4weeks on a thrice weekly basis, with a follow up WAB 
      performed at four and twelve weeks after baseline assessment. The trial was 
      registered with Clinical trials registry India [2016/08/0120121]. STATISTICAL 
      ANALYSIS: All the statistical analysis was carried out with IBM SPSS Statistics 
      for Windows version 21. RESULTS: 20 subjects [14 (70%) Males; Mean age: 
      52.8years+/-SD12.04] completed the study (9 in the less intensive and 11 in the 
      more intensive arm). The mean four weeks follow up AQ showed a significant 
      improvement from the baseline in the total group (p value: 0.01). The rate of 
      rise of AQ from the baseline to four weeks follow up (DeltaAQ %) showed a 
      significantly greater value for the less intensive treatment group as against the 
      more intensive treatment group [155% (SD: 150; 95% CI: 34-275) versus 52% (SD: 
      42%; 95% CI: 24-80) respectively: p value: 0.053]. CONCLUSIONS: Even though the 
      more intensive treatment arm incorporating combined professional based SLT and 
      computer software based training fared poorer than the less intensive therapy 
      group, this study nevertheless reinforces the feasibility of SLT in augmenting 
      recovery of early post stroke aphasia.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Kesav, Praveen
AU  - Kesav P
AD  - Comprehensive Stroke Care Program, Department of Neurology, Sree Chitra Tirunal 
      Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695011, 
      India.
FAU - Vrinda, S L
AU  - Vrinda SL
AD  - Comprehensive Stroke Care Program, Department of Neurology, Sree Chitra Tirunal 
      Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695011, 
      India.
FAU - Sukumaran, Sajith
AU  - Sukumaran S
AD  - Comprehensive Stroke Care Program, Department of Neurology, Sree Chitra Tirunal 
      Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695011, 
      India.
FAU - Sarma, P S
AU  - Sarma PS
AD  - Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute 
      for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695011, India.
FAU - Sylaja, P N
AU  - Sylaja PN
AD  - Comprehensive Stroke Care Program, Department of Neurology, Sree Chitra Tirunal 
      Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695011, 
      India. Electronic address: sylajapn@sctimst.ac.in.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20170708
PL  - Netherlands
TA  - J Neurol Sci
JT  - Journal of the neurological sciences
JID - 0375403
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aphasia/*etiology/*rehabilitation
MH  - Chronic Disease
MH  - Combined Modality Therapy
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - India
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - *Software
MH  - Speech Therapy/*instrumentation/*methods
MH  - Stroke/*complications
MH  - Stroke Rehabilitation
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Aphasia
OT  - Computer therapy
OT  - Outcome
OT  - Speech therapy
EDAT- 2017/09/06 06:00
MHDA- 2018/05/09 06:00
CRDT- 2017/09/06 06:00
PHST- 2017/01/17 00:00 [received]
PHST- 2017/07/05 00:00 [revised]
PHST- 2017/07/06 00:00 [accepted]
PHST- 2017/09/06 06:00 [entrez]
PHST- 2017/09/06 06:00 [pubmed]
PHST- 2018/05/09 06:00 [medline]
AID - S0022-510X(17)30444-6 [pii]
AID - 10.1016/j.jns.2017.07.010 [doi]
PST - ppublish
SO  - J Neurol Sci. 2017 Sep 15;380:137-141. doi: 10.1016/j.jns.2017.07.010. Epub 2017 
      Jul 8.