PMID- 2887995
OWN - NLM
STAT- MEDLINE
DCOM- 19871006
LR  - 20190701
IS  - 0024-3205 (Print)
IS  - 0024-3205 (Linking)
VI  - 41
IP  - 11
DP  - 1987 Sep 14
TI  - Behavioral suppression following 3,4-methylenenedioxymethamphetamine.
PG  - 1425-9
AB  - Rotation in rats was employed as an assay of the central dopaminergic activity of 
      3,4-methylenedioxymethamphetamine (MDMA). This agent was observed to possess 
      predominantly amphetamine-like actions at low doses. However, at higher doses it 
      also appears to stimulate the dopamine receptor directly. Following a third dose 
      of MDMA, a significant decrease in rotation was evident to this drug and to 
      amphetamine, suggesting a neurotoxic or long-term suppressive action of MDMA.
FAU - Kulmala, H K
AU  - Kulmala HK
FAU - Boja, J W
AU  - Boja JW
FAU - Schechter, M D
AU  - Schechter MD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Life Sci
JT  - Life sciences
JID - 0375521
RN  - 0 (Amphetamines)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
RN  - TZ47U051FI (Dextroamphetamine)
SB  - IM
MH  - 3,4-Methylenedioxyamphetamine/analogs & derivatives/*pharmacology
MH  - Amphetamines/*pharmacology
MH  - Animals
MH  - Behavior, Animal/*drug effects
MH  - Dextroamphetamine/pharmacology
MH  - Male
MH  - Motor Activity/drug effects
MH  - N-Methyl-3,4-methylenedioxyamphetamine
MH  - Rats
EDAT- 1987/09/14 00:00
MHDA- 1987/09/14 00:01
CRDT- 1987/09/14 00:00
PHST- 1987/09/14 00:00 [pubmed]
PHST- 1987/09/14 00:01 [medline]
PHST- 1987/09/14 00:00 [entrez]
AID - 0024-3205(87)90618-7 [pii]
AID - 10.1016/0024-3205(87)90618-7 [doi]
PST - ppublish
SO  - Life Sci. 1987 Sep 14;41(11):1425-9. doi: 10.1016/0024-3205(87)90618-7.