PMID- 28883243 OWN - NLM STAT- MEDLINE DCOM- 20180402 LR - 20181202 IS - 1349-7235 (Electronic) IS - 0918-2918 (Print) IS - 0918-2918 (Linking) VI - 56 IP - 19 DP - 2017 Oct 1 TI - An HIV-positive Case of Obstructive Jaundice Caused by Immune Reconstitution Inflammatory Syndrome of Tuberculous Lymphadenitis Successfully Treated with Corticosteroids. PG - 2661-2666 LID - 10.2169/internalmedicine.8713-16 [doi] AB - A 60-year-old man was admitted to our hospital because of a persistent fever with enlargement of multiple lymph nodes in the mediastinum and around the pancreatic head. He was diagnosed with tuberculosis and human immunodeficiency virus infection. We started antiretroviral therapy three weeks after the initiation of anti-tuberculous therapy. Two weeks later, jaundice appeared with dilatation of the biliary tract due to further enlargement of the lymph nodes, which seemed to be immune reconstitution inflammatory syndrome (IRIS). The administration of corticosteroids resolved the obstructive jaundice without surgical treatment or endoscopic drainage. Obstructive jaundice caused by IRIS should first be treated with corticosteroids before invasive treatment. FAU - Watanabe, Naoaki AU - Watanabe N AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Sato, Ryota AU - Sato R AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Nagai, Hideaki AU - Nagai H AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Matsui, Hirotoshi AU - Matsui H AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Yamane, Akira AU - Yamane A AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Kawashima, Masahiro AU - Kawashima M AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Suzuki, Junko AU - Suzuki J AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Tashimo, Hiroyuki AU - Tashimo H AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Ohshima, Nobuharu AU - Ohshima N AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Masuda, Kimihiko AU - Masuda K AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Tamura, Atsuhisa AU - Tamura A AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Akagawa, Shinobu AU - Akagawa S AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. FAU - Hebisawa, Akira AU - Hebisawa A AD - Department of Clinical Research, National Hospital Organization Tokyo National Hospital, Japan. FAU - Ohta, Ken AU - Ohta K AD - Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. LA - eng PT - Case Reports PT - Journal Article DEP - 20170906 PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 RN - 0 (Adrenal Cortex Hormones) RN - 0 (Anti-Retroviral Agents) SB - IM MH - Adrenal Cortex Hormones/*therapeutic use MH - Anti-Retroviral Agents/*therapeutic use MH - HIV Infections/complications/*drug therapy MH - HIV Seropositivity/complications MH - Humans MH - Immune Reconstitution Inflammatory Syndrome/*complications/diagnosis/*drug therapy MH - Jaundice, Obstructive/*drug therapy/etiology MH - Lymph Nodes/pathology MH - Male MH - Middle Aged MH - Treatment Outcome MH - Tuberculosis, Lymph Node/*drug therapy PMC - PMC5658536 OTO - NOTNLM OT - HIV OT - immune reconstitution inflammatory syndrome OT - obstructive jaundice OT - tuberculous lymphadenitis EDAT- 2017/09/09 06:00 MHDA- 2018/04/03 06:00 PMCR- 2017/10/01 CRDT- 2017/09/09 06:00 PHST- 2017/09/09 06:00 [pubmed] PHST- 2018/04/03 06:00 [medline] PHST- 2017/09/09 06:00 [entrez] PHST- 2017/10/01 00:00 [pmc-release] AID - 10.2169/internalmedicine.8713-16 [doi] PST - ppublish SO - Intern Med. 2017 Oct 1;56(19):2661-2666. doi: 10.2169/internalmedicine.8713-16. Epub 2017 Sep 6.