PMID- 28892878
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2249-782X (Print)
IS  - 0973-709X (Electronic)
IS  - 0973-709X (Linking)
VI  - 11
IP  - 7
DP  - 2017 Jul
TI  - Role of Anthropometric Measurements in Development of CVD and Stroke among T2DM 
      in East Godavari District, Andhra Pradesh, India.
PG  - BC01-BC05
LID - 10.7860/JCDR/2017/25536.10165 [doi]
AB  - INTRODUCTION: Cardiovascular morbidity and mortality have been associated with 
      different variables of anthropometric measurements. AIM: To find out the 
      association of anthropometric measurements in the development of Cardiovascular 
      Disease (CVD) and stroke among Type 2 Diabetes Mellitus (T2DM). MATERIALS AND 
      METHODS: Three hundred subjects were included in the study out of which 100 
      subjects were known type 2 diabetics with CVD or Stroke (Group 1), 100 subjects 
      were type 2 diabetic patients (Group 2) and 100 subjects were normal and healthy 
      (Group 3). Blood Pressure (BP), Body Mass Index (BMI) Neck Circumference (NC), 
      Waist Circumference (WC), Hip Circumference (HC), Glycated haemoglobin (HbA1c), 
      high sensitive- C-Reactive Protein (hsCRP), Malondialdehyde (MDA), Homocysteine 
      (Hcy), microalbuminuria and estimated glomerular filtration rate (eGFR) were 
      compared between all three groups by using one-way ANOVA test, comparison between 
      males and females by t-test and association was done by using Chi-square test. 
      RESULTS: There were a significant difference in the means of anthropometric and 
      biochemical parameters of the three groups (p<0.05). Diastolic BP, NC, WC, HC and 
      homocysteine, are higher in T2DM obese patients than T2DM over weight and normal 
      weight patients are statistically significant (p<0.05). The mean of levels 
      systolic BP, Diastolic BP, hsCRP are higher in T2DM over weight patients than 
      T2DM obese and normal weight patients are statistically significant (p<0.05). 
      Association of physical activity, snoring and interrupted sleep with BMI was 
      statistical significant (p<0.05). CONCLUSION: Obesity and overweight in T2DM 
      patients play important role in elevation of blood pressure and inflammation 
      markers like hsCRP, homocysteine. Snoring and interrupted sleep also involved 
      development of CVD and Stroke among T2 diabetes.
FAU - Deedi, Mortha Kiran
AU  - Deedi MK
AD  - Research Scholar, School of Life and Health Sciences, Adikavi Nannaya University, 
      Rajahmundry, Andhra Pradesh, India; Department of Biochemistry, GSL Medical 
      College, Rajahmundry, Andhra Pradesh, India.
FAU - Reddy, Alavala Matta
AU  - Reddy AM
AD  - Associate Professor, School of Life and Health Sciences, Adikavi Nannaya 
      University, Rajahmundry, Andhra Pradesh, India.
FAU - Kumar, Nelakuditi Lakshmana
AU  - Kumar NL
AD  - Professor and Head, Department of Biochemistry, GSL Medical College and General 
      Hospital, Rajahmundry, Andhra Pradesh, India.
LA  - eng
PT  - Journal Article
DEP - 20170701
PL  - India
TA  - J Clin Diagn Res
JT  - Journal of clinical and diagnostic research : JCDR
JID - 101488993
PMC - PMC5583876
OTO - NOTNLM
OT  - Body mass index
OT  - Diabetic complications
OT  - Obesity
EDAT- 2017/09/13 06:00
MHDA- 2017/09/13 06:01
PMCR- 2017/07/01
CRDT- 2017/09/13 06:00
PHST- 2016/11/23 00:00 [received]
PHST- 2017/04/21 00:00 [accepted]
PHST- 2017/09/13 06:00 [entrez]
PHST- 2017/09/13 06:00 [pubmed]
PHST- 2017/09/13 06:01 [medline]
PHST- 2017/07/01 00:00 [pmc-release]
AID - 10.7860/JCDR/2017/25536.10165 [doi]
PST - ppublish
SO  - J Clin Diagn Res. 2017 Jul;11(7):BC01-BC05. doi: 10.7860/JCDR/2017/25536.10165. 
      Epub 2017 Jul 1.