PMID- 28893082 OWN - NLM STAT- MEDLINE DCOM- 20190102 LR - 20190102 IS - 1940-1574 (Electronic) IS - 0003-3197 (Linking) VI - 69 IP - 5 DP - 2018 May TI - Relation Between TRCA Complication Rates and Peak ACT Levels Stratified According to the BMI Tertiles. PG - 400-405 LID - 10.1177/0003319717729289 [doi] AB - We evaluated the efficacy and safety of the fixed dose of 5000 IU unfractionated heparin (UFH) represented as peak activated clotting time (ACT) according to the body mass index (BMI) tertiles in patients undergoing diagnostic transradial coronary angiography (TRCA). A total of 422 patients were included in the present study, 84 in the normal weight group, 218 in the overweight group, and the 120 in the grades 1 and 2 obesity groups. Radial artery occlusion (RAO) was observed in 29 (6.8%) patients and the hematoma was observed in 43 (10.1%) patients. The rate of RAO and hematoma did not differ across the BMI tertiles ( P = .749 and P = .066). Also, peak ACT and procedure duration did not differ between the study groups ( P = .703 and P = .999). The only independent predictor of hematoma was sheath/radial artery diameter ( P = .011) and the independent predictors for RAO were peak ACT, sheath/radial artery diameter, and procedure duration ( P = .001, P = .028, and P < .001, respectively). In conclusion, a fixed dose of 5000 IU UFH is safe and effective regardless of the BMI in diagnostic TRCA procedure. FAU - Balci, Kevser Gulcihan AU - Balci KG AD - 1 Turkiye Yuksek Ihtisas Research and Education Hospital, Altindag, Ankara, Turkey. FAU - Maden, Orhan AU - Maden O AD - 1 Turkiye Yuksek Ihtisas Research and Education Hospital, Altindag, Ankara, Turkey. FAU - Balci, Mustafa Mucahit AU - Balci MM AD - 1 Turkiye Yuksek Ihtisas Research and Education Hospital, Altindag, Ankara, Turkey. FAU - Cetin, Elif Hande AU - Cetin EH AD - 1 Turkiye Yuksek Ihtisas Research and Education Hospital, Altindag, Ankara, Turkey. FAU - Kafes, Habibe AU - Kafes H AD - 1 Turkiye Yuksek Ihtisas Research and Education Hospital, Altindag, Ankara, Turkey. FAU - Tola, Muharrem AU - Tola M AD - 1 Turkiye Yuksek Ihtisas Research and Education Hospital, Altindag, Ankara, Turkey. FAU - Selcuk, Hatice AU - Selcuk H AD - 1 Turkiye Yuksek Ihtisas Research and Education Hospital, Altindag, Ankara, Turkey. FAU - Selcuk, Mehmet Timur AU - Selcuk MT AD - 1 Turkiye Yuksek Ihtisas Research and Education Hospital, Altindag, Ankara, Turkey. LA - eng PT - Journal Article DEP - 20170912 PL - United States TA - Angiology JT - Angiology JID - 0203706 RN - 0 (Fibrinolytic Agents) RN - 9005-49-6 (Heparin) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Arterial Occlusive Diseases/diagnosis/*etiology MH - Body Mass Index MH - Coronary Angiography/*adverse effects MH - Female MH - Fibrinolytic Agents/therapeutic use MH - Hematoma/diagnosis/*etiology MH - Heparin/therapeutic use MH - Humans MH - Male MH - Middle Aged MH - Obesity/*complications MH - *Radial Artery MH - Sensitivity and Specificity MH - *Whole Blood Coagulation Time OTO - NOTNLM OT - activated clotting time OT - body mass index OT - complication OT - heparin OT - radial angiography EDAT- 2017/09/13 06:00 MHDA- 2019/01/03 06:00 CRDT- 2017/09/13 06:00 PHST- 2017/09/13 06:00 [pubmed] PHST- 2019/01/03 06:00 [medline] PHST- 2017/09/13 06:00 [entrez] AID - 10.1177/0003319717729289 [doi] PST - ppublish SO - Angiology. 2018 May;69(5):400-405. doi: 10.1177/0003319717729289. Epub 2017 Sep 12.