PMID- 28900882 OWN - NLM STAT- MEDLINE DCOM- 20180706 LR - 20201209 IS - 1573-0832 (Electronic) IS - 0301-486X (Linking) VI - 182 IP - 11-12 DP - 2017 Dec TI - Acute Paracoccidioidomycosis in a 40-Year-Old Man: A Case Report and Literature Review. PG - 1095-1099 LID - 10.1007/s11046-017-0196-7 [doi] AB - Paracoccidioidomycosis (PCM) is a systemic mycosis that represents an important public health problem in Latin America due to its life-threatening character. It is considered occupational disease of agricultural workers. In this report, we present a rare and serious case of the acute form of the disease in a 40-year-old man with no history of contact with the rural environment. Diagnosis was made through cervical lymph node biopsy, and treatment was performed with antifungal drugs, which produced effective results. A literature review was conducted with discussion of clinical, pathophysiological and therapeutic aspects of PCM. FAU - Ferreira Rocha, Lucas AU - Ferreira Rocha L AD - Department of Otolaryngology, Lagoa's Hospital, 501 Jardim Botanico Street, Rio de Janeiro, RJ, 22470-050, Brazil. lucasunimontes@yahoo.com.br. FAU - de Araujo Torres, Danielle AU - de Araujo Torres D AD - Department of Otolaryngology, Lagoa's Hospital, 501 Jardim Botanico Street, Rio de Janeiro, RJ, 22470-050, Brazil. LA - eng PT - Case Reports PT - Journal Article PT - Review DEP - 20170912 PL - Netherlands TA - Mycopathologia JT - Mycopathologia JID - 7505689 RN - 0 (Antifungal Agents) RN - 304NUG5GF4 (Itraconazole) RN - 7XU7A7DROE (Amphotericin B) RN - 8064-90-2 (Trimethoprim, Sulfamethoxazole Drug Combination) SB - IM MH - Adult MH - Amphotericin B/*therapeutic use MH - Antifungal Agents/*therapeutic use MH - Biopsy MH - Brazil MH - Humans MH - Itraconazole/*therapeutic use MH - Lymph Node Excision MH - Male MH - Paracoccidioides/*isolation & purification MH - Paracoccidioidomycosis/*diagnosis/*drug therapy/microbiology MH - Trimethoprim, Sulfamethoxazole Drug Combination/*therapeutic use OTO - NOTNLM OT - Differential diagnosis OT - Lymph node excision OT - Mycoses OT - Otolaryngology OT - Paracoccidioidomycosis EDAT- 2017/09/14 06:00 MHDA- 2018/07/07 06:00 CRDT- 2017/09/14 06:00 PHST- 2017/05/21 00:00 [received] PHST- 2017/08/18 00:00 [accepted] PHST- 2017/09/14 06:00 [pubmed] PHST- 2018/07/07 06:00 [medline] PHST- 2017/09/14 06:00 [entrez] AID - 10.1007/s11046-017-0196-7 [pii] AID - 10.1007/s11046-017-0196-7 [doi] PST - ppublish SO - Mycopathologia. 2017 Dec;182(11-12):1095-1099. doi: 10.1007/s11046-017-0196-7. Epub 2017 Sep 12.