PMID- 28903248
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1424-8220 (Electronic)
IS  - 1424-8220 (Linking)
VI  - 7
IP  - 11
DP  - 2007 Nov 2
TI  - Biochemical Markers for Assessing Aquatic Contamination.
PG  - 2599-2611
LID - 10.3390/s7112599 [doi]
AB  - Biochemical markers, specifically enzymes of the first phase of xenobiotic 
      transformation - cytochrome P450 and ethoxyresorufin-O-deethylase (EROD) - were 
      used to determine the quantities of persistent organic pollutants (POPs) in fish 
      muscle (PCB, HCB, HCH, OCS, DDT). Eight rivers were monitored (Orlice, Chrudimka, 
      Cidlina, Jizera, Vltava, Ohre and Bilina; and the River Blanice was used as a 
      control). The indicator species selected was the chub (Leuciscus cephalus L.). 
      There were no significant differences in cytochrome P450 content between the 
      locations monitored. The highest concentration of cytochrome P450 in fish liver 
      was in the Vltava (0.241 nmol mg-1 protein), and the lowest was in the Orlice 
      (0.120 nmol mg-1 protein). Analysis of EROD activity showed a significant 
      difference between the Blanice and the Vltava (P< 0.05), and also between the 
      Orlice and the Vltava (P< 0.01), the Orlice and the Bilina (P< 0.01), and the 
      Orlice and the Ohre (P< 0.05). The highest EROD activity in fish liver was in the 
      Vltava (576.4 pmol min-1 mg-1 protein), and the lowest was in the Orlice (63.05 
      pmol min-1 mg-1 protein). In individual locations, results of chemical monitoring 
      and values of biochemical markers were compared. A significant correlation (P< 
      0.05) was found between biochemical markers and OCS, and PCB. Among the 
      tributaries studied those that contaminated the Elbe most were the Vltava and the 
      Bilina. These tributaries should not be considered the main sources of industrial 
      contamination of the River Elbe, because the most important contamination sources 
      were along the river Elbe itself.
FAU - Havelkova, Marcela
AU  - Havelkova M
AD  - University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary 
      Hygiene and Ecology, Palackeho 1-3, 612 42 Brno, Czech Republic. 
      mhavelkova@vfu.cz.
FAU - Randak, Tomas
AU  - Randak T
AD  - University of South Bohemia Ceske Budejovice, Research Institute of Fish Culture 
      and Hydrobiology Vodnany, Zatisi 728/II, 389 25 Vodnany, Czech Republic.
FAU - Zlabek, Vladimir
AU  - Zlabek V
AD  - University of South Bohemia Ceske Budejovice, Research Institute of Fish Culture 
      and Hydrobiology Vodnany, Zatisi 728/II, 389 25 Vodnany, Czech Republic.
FAU - Krijt, Jan
AU  - Krijt J
AD  - Charles University, First Faculty of Medicine, Institute of Pathological 
      Physiology, U Nemocnice 5, 128 53 Praha 2, Czech Republic.
FAU - Kroupova, Hana
AU  - Kroupova H
AD  - University of South Bohemia Ceske Budejovice, Research Institute of Fish Culture 
      and Hydrobiology Vodnany, Zatisi 728/II, 389 25 Vodnany, Czech Republic.
FAU - Pulkrabova, Jana
AU  - Pulkrabova J
AD  - Institute of Chemical Technology Prague, Department of Food Chemistry and 
      Analysis, Technicka 3, 166 28 Praha 6, Czech Republic.
FAU - Svobodova, Zdenka
AU  - Svobodova Z
AD  - University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary 
      Hygiene and Ecology, Palackeho 1-3, 612 42 Brno, Czech Republic.
LA  - eng
PT  - Journal Article
DEP - 20071102
PL  - Switzerland
TA  - Sensors (Basel)
JT  - Sensors (Basel, Switzerland)
JID - 101204366
PMC - PMC3965215
OTO - NOTNLM
OT  - EROD
OT  - Leuciscus cephalus L.
OT  - River Elbe
OT  - cytochrome P450
OT  - persistent organic pollutants
EDAT- 2007/11/02 00:00
MHDA- 2007/11/02 00:01
PMCR- 2007/11/01
CRDT- 2017/09/15 06:00
PHST- 2007/09/18 00:00 [received]
PHST- 2007/11/01 00:00 [accepted]
PHST- 2017/09/15 06:00 [entrez]
PHST- 2007/11/02 00:00 [pubmed]
PHST- 2007/11/02 00:01 [medline]
PHST- 2007/11/01 00:00 [pmc-release]
AID - s7112599 [pii]
AID - sensors-07-02599 [pii]
AID - 10.3390/s7112599 [doi]
PST - epublish
SO  - Sensors (Basel). 2007 Nov 2;7(11):2599-2611. doi: 10.3390/s7112599.