PMID- 28904852 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 2210-9099 (Print) IS - 2233-6052 (Electronic) IS - 2210-9099 (Linking) VI - 8 IP - 4 DP - 2017 Aug TI - Seroprevalence of Brucellosis in Human Immunodeficiency Virus Infected Patients in Hamadan, Iran. PG - 282-288 LID - 10.24171/j.phrp.2017.8.4.09 [doi] AB - OBJECTIVES: Brucellosis is a systemic disease with a wide spectrum of clinical manifestations. This study aimed to determine the seroprevalence of brucellosis in human immunodeficiency virus (HIV) infected patients in Hamadan Province in the west of Iran. METHODS: A total of 157 HIV-infected patients were screened through standard serological tests, including Wright's test, Coombs' Wright test, and 2-mercaptoethanol Brucella agglutination test (2ME test), blood cultures in Castaneda media, and CD4 counting. Data were analyzed using Stata version 11. RESULTS: Wright and Coombs' Wright tests were carried out, and only 5 (3.2%) patients had positive serological results. However, all patients had negative 2ME results, and blood cultures were negative for Brucella spp. Moreover, patients with positive serology and a mean CD4 count of 355.8 +/- 203.11 cells/muL had no clinical manifestations of brucellosis, and, and the other patients had a mean CD4 count of 335.55 +/- 261.71 cells/muL. CONCLUSION: Results of this study showed that HIV infection is not a predisposing factor of acquiring brucellosis. FAU - Keramat, Fariba AU - Keramat F AD - Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. FAU - Majzobi, Mohammad Mehdi AU - Majzobi MM AD - Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. FAU - Poorolajal, Jalal AU - Poorolajal J AD - Departments of Epidemiology and Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran. FAU - Ghane, Zohreh Zarei AU - Ghane ZZ AD - Reference Laboratory of the Health Centre, Hamadan, Iran. FAU - Adabi, Maryam AU - Adabi M AD - Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. LA - eng PT - Journal Article DEP - 20170831 PL - Korea (South) TA - Osong Public Health Res Perspect JT - Osong public health and research perspectives JID - 101563309 PMC - PMC5594717 OTO - NOTNLM OT - brucellosis OT - human immunodeficiency virus OT - serology COIS- CONFLICTS OF INTEREST No potential conflict of interest relevant to this article was reported. EDAT- 2017/09/15 06:00 MHDA- 2017/09/15 06:01 PMCR- 2017/08/01 CRDT- 2017/09/15 06:00 PHST- 2017/07/10 00:00 [received] PHST- 2017/08/10 00:00 [revised] PHST- 2017/08/22 00:00 [accepted] PHST- 2017/09/15 06:00 [entrez] PHST- 2017/09/15 06:00 [pubmed] PHST- 2017/09/15 06:01 [medline] PHST- 2017/08/01 00:00 [pmc-release] AID - phrp-08-282 [pii] AID - 10.24171/j.phrp.2017.8.4.09 [doi] PST - ppublish SO - Osong Public Health Res Perspect. 2017 Aug;8(4):282-288. doi: 10.24171/j.phrp.2017.8.4.09. Epub 2017 Aug 31.