PMID- 28911564
OWN - NLM
STAT- MEDLINE
DCOM- 20171218
LR  - 20220809
IS  - 2224-6614 (Electronic)
IS  - 1021-9498 (Print)
VI  - 24
IP  - 3
DP  - 2016 Jul
TI  - Trace residue analysis of dicyandiamide, cyromazine, and melamine in animal 
      tissue foods by ultra-performance liquid chromatography.
PG  - 579-585
LID - 10.1016/j.jfda.2016.01.003 [doi]
AB  - An effective sample preparation procedure using an accelerated solvent extraction 
      (ASE) procedure, followed by cleaning with melamine molecularly imprinted 
      polymers solid-phase extraction (MISPE) was developed. A novel and highly 
      sensitive ASE-MISPE-ultra-performance liquid chromatography (UPLC) method was 
      developed for effective separation and simultaneous determination of 
      dicyandiamide (DCD), cyromazine (CYR), and melamine (MEL) in complex animal 
      tissue foods. Under optimized conditions, good linearity was achieved with a 
      correlation coefficient (r) of 0.9999 in the range of at least two orders of 
      magnitude. The limit of quantification of the method was 1.7 mug/kg, 5.0 mug/kg, 
      and 3.2 mug/kg for DCD, MEL, and CYR, which was three orders of magnitude smaller 
      than the maximum residue limits (MRLs). The intra- and inter-day precisions (in 
      terms of the relative standard deviation, RSD) of the three analytes were in the 
      range of 1.7-3.1% and 3.1-6.3%, respectively. The average recoveries of analytes 
      from blank chicken, beef, mutton, pork, and pig liver samples spiked with the 
      three levels varied from 91.2% to 107% with RSD of 1.7-8.3% for DCD, 89.0-104% 
      with RSD of 2.1-6.1% for CYR, and 94.8-105% with RSD of 1.1-6.6% for MEL. The 
      proposed method has the characteristics of speed, sensitivity, and accuracy, and 
      can be used for the routine determination of DCD, CYR, and MEL at the mug/kg level 
      in complex animal tissue foods.
CI  - Copyright (c) 2016. Published by Elsevier B.V.
FAU - Ge, Xusheng
AU  - Ge X
AD  - College of Chemistry and Environmental Science, Hebei University, Key Laboratory 
      of Analytical Science and Technology of Hebei Province, Baoding, 071002, China.
AD  - Biochemical Department, Baoding University, Baoding, 071000, China.
FAU - Wu, Xingqiang
AU  - Wu X
AD  - College of Chemistry and Environmental Science, Hebei University, Key Laboratory 
      of Analytical Science and Technology of Hebei Province, Baoding, 071002, China.
FAU - Liang, Shuxuan
AU  - Liang S
AD  - College of Chemistry and Environmental Science, Hebei University, Key Laboratory 
      of Analytical Science and Technology of Hebei Province, Baoding, 071002, China.
FAU - Su, Ming
AU  - Su M
AD  - College of Chemistry and Environmental Science, Hebei University, Key Laboratory 
      of Analytical Science and Technology of Hebei Province, Baoding, 071002, China.
FAU - Sun, Hanwen
AU  - Sun H
AD  - College of Chemistry and Environmental Science, Hebei University, Key Laboratory 
      of Analytical Science and Technology of Hebei Province, Baoding, 071002, China.
LA  - eng
PT  - Journal Article
DEP - 20160223
PL  - China (Republic : 1949- )
TA  - J Food Drug Anal
JT  - Journal of food and drug analysis
JID - 101630927
RN  - 0 (Guanidines)
RN  - 0 (Triazines)
RN  - CA49Y29RA9 (cyromazine)
RN  - M9B1R0C16H (dicyandiamido)
RN  - N3GP2YSD88 (melamine)
SB  - IM
MH  - Animals
MH  - Chromatography, Liquid
MH  - Guanidines/*analysis
MH  - Milk
MH  - Red Meat
MH  - Swine
MH  - Triazines/*analysis
PMC - PMC9336660
OTO - NOTNLM
OT  - animal tissue foods
OT  - cyromazine
OT  - dicyandiamide
OT  - melamine
OT  - ultra-performance liquid chromatography
COIS- Conflicts of interest All contributing authors declare no conflicts of interest.
EDAT- 2016/07/01 00:00
MHDA- 2017/12/19 06:00
PMCR- 2016/02/23
CRDT- 2017/09/16 06:00
PHST- 2015/10/28 00:00 [received]
PHST- 2016/01/08 00:00 [revised]
PHST- 2016/01/21 00:00 [accepted]
PHST- 2017/09/16 06:00 [entrez]
PHST- 2016/07/01 00:00 [pubmed]
PHST- 2017/12/19 06:00 [medline]
PHST- 2016/02/23 00:00 [pmc-release]
AID - j.jfda.2016.01.003 [pii]
AID - jfda-24-03-579 [pii]
AID - 10.1016/j.jfda.2016.01.003 [doi]
PST - ppublish
SO  - J Food Drug Anal. 2016 Jul;24(3):579-585. doi: 10.1016/j.jfda.2016.01.003. Epub 
      2016 Feb 23.