PMID- 28914589
OWN - NLM
STAT- MEDLINE
DCOM- 20171121
LR  - 20191210
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 34
IP  - 12
DP  - 2017 Dec
TI  - HPLC-DAD method development and validation for the quantification of 
      hydroxymethylfurfural in corn chips by means of response surface optimisation.
PG  - 2101-2110
LID - 10.1080/19440049.2017.1380316 [doi]
AB  - In recent years, there has been an increased concern about the presence of toxic 
      compounds derived from the Maillard reaction produced during food cooking at high 
      temperatures. The main toxic compounds derived from this reaction are acrylamide 
      and hydroxymethylfurfural (HMF). The majority of analytical methods require 
      sample treatments using solvents which are highly polluting for the environment. 
      The difficulty of quantifying HMF in complex fried food matrices encourages the 
      development of new analytical methods. This paper provides a rapid, sensitive and 
      environmentally-friendly analytical method for the quantification of HMF in corn 
      chips using HPLC-DAD. Chromatographic separation resulted in a baseline 
      separation for HMF in 3.7 min. Sample treatment for corn chip samples first 
      involved a leaching process using water and afterwards a solid-phase extraction 
      (SPE) using HLB-Oasis polymeric cartridges. Sample treatment optimisation was 
      carried out by means of Box-Behnken fractional factorial design and Response 
      Surface Methodolog y to examine the effects of four variables (sample weight, pH, 
      sonication time and elution volume) on HMF extraction from corn chips. The 
      SPE-HPLC-DAD method was validated. The limits of detection and quantification 
      were 0.82 and 2.20 mg kg(-1), respectively. Method precision was evaluated in 
      terms of repeatability and reproducibility as relative standard deviations (RSDs) 
      using three concentration levels. For repeatability, RSD values were 6.9, 3.6 and 
      2.0%; and for reproducibility 18.8, 7.9 and 2.9%. For a ruggedness study the 
      Yuden test was applied and the result demonstrated the method as robust. The 
      method was successfully applied to different corn chip samples.
FAU - Salvatierra Virgen, Sara
AU  - Salvatierra Virgen S
AD  - a Facultad de Ciencias Quimicas , Universidad de Colima , Carretera 
      Colima-Coquimatlan km 9, 28400 , Coquimatlan , Colima , Mexico.
FAU - Ceballos-Magana, Silvia Guillermina
AU  - Ceballos-Magana SG
AD  - b Facultad de Ciencias , Universidad de Colima , Bernal Diaz del Castillo 340, 
      28045 , Colima , Colima , Mexico.
FAU - Salvatierra-Stamp, Vilma Del Carmen
AU  - Salvatierra-Stamp VDC
AD  - a Facultad de Ciencias Quimicas , Universidad de Colima , Carretera 
      Colima-Coquimatlan km 9, 28400 , Coquimatlan , Colima , Mexico.
FAU - Sumaya-Martinez, Maria Teresa
AU  - Sumaya-Martinez MT
AD  - c Unidad de Biotecnologia y Productos Funcionales , Universidad Autonoma de 
      Nayarit , Ciudad de la Cultura Amado Nervo, 63155 , Tepic , Mexico.
FAU - Martinez-Martinez, Francisco Javier
AU  - Martinez-Martinez FJ
AD  - a Facultad de Ciencias Quimicas , Universidad de Colima , Carretera 
      Colima-Coquimatlan km 9, 28400 , Coquimatlan , Colima , Mexico.
FAU - Muniz-Valencia, Roberto
AU  - Muniz-Valencia R
AD  - a Facultad de Ciencias Quimicas , Universidad de Colima , Carretera 
      Colima-Coquimatlan km 9, 28400 , Coquimatlan , Colima , Mexico.
LA  - eng
PT  - Journal Article
PT  - Validation Study
DEP - 20170928
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 70ETD81LF0 (5-hydroxymethylfurfural)
RN  - DJ1HGI319P (Furaldehyde)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - Food Contamination/*analysis
MH  - Furaldehyde/*analogs & derivatives/analysis
MH  - Surface Properties
MH  - Zea mays/*chemistry
OTO - NOTNLM
OT  - Box-Behnken fractional factorial design
OT  - HPLC-DAD
OT  - Hydroxymethylfurfural
OT  - Response Surface Methodology
OT  - corn chips
EDAT- 2017/09/16 06:00
MHDA- 2017/11/29 06:00
CRDT- 2017/09/16 06:00
PHST- 2017/09/16 06:00 [pubmed]
PHST- 2017/11/29 06:00 [medline]
PHST- 2017/09/16 06:00 [entrez]
AID - 10.1080/19440049.2017.1380316 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 
      Dec;34(12):2101-2110. doi: 10.1080/19440049.2017.1380316. Epub 2017 Sep 28.