PMID- 28916232
OWN - NLM
STAT- MEDLINE
DCOM- 20180612
LR  - 20180809
IS  - 1471-4981 (Electronic)
IS  - 1471-4906 (Linking)
VI  - 38
IP  - 11
DP  - 2017 Nov
TI  - Circulating Normal IgG as Stimulator of Regulatory T Cells: Lessons from 
      Intravenous Immunoglobulin.
PG  - 789-792
LID - S1471-4906(17)30172-2 [pii]
LID - 10.1016/j.it.2017.08.008 [doi]
AB  - Intravenous immunoglobulin (IVIG), a pooled normal IgG formulation prepared from 
      thousands of healthy donors' plasma, is extensively used for the immunotherapy of 
      autoimmune and inflammatory disorders. Recent reports demonstrate that IVIG 
      exerts anti-inflammatory actions by stimulating the activation and expansion of 
      regulatory T (Treg) cells by multiple mechanisms via antigen-presenting cells 
      (APCs).
CI  - Copyright (c) 2017 Elsevier Ltd. All rights reserved.
FAU - Maddur, Mohan S
AU  - Maddur MS
AD  - Institut National de la Sante et de la Recherche Medicale Unite 1138, Paris, 
      F-75006, France; Centre de Recherche des Cordeliers, Equipe-Immunopathologie et 
      Immunointervention Therapeutique, Paris, F-75006, France; Sorbonne Universites, 
      UPMC University Paris 06, UMR S 1138, Paris, F-75006, France; Present Address: 
      Pfizer Inc, Pearl River, NY, USA.
FAU - Kaveri, Srini V
AU  - Kaveri SV
AD  - Institut National de la Sante et de la Recherche Medicale Unite 1138, Paris, 
      F-75006, France; Centre de Recherche des Cordeliers, Equipe-Immunopathologie et 
      Immunointervention Therapeutique, Paris, F-75006, France; Sorbonne Universites, 
      UPMC University Paris 06, UMR S 1138, Paris, F-75006, France; Universite Paris 
      Descartes, Sorbonne Paris Cite, UMR S 1138, Paris, F-75006, France.
FAU - Bayry, Jagadeesh
AU  - Bayry J
AD  - Institut National de la Sante et de la Recherche Medicale Unite 1138, Paris, 
      F-75006, France; Centre de Recherche des Cordeliers, Equipe-Immunopathologie et 
      Immunointervention Therapeutique, Paris, F-75006, France; Sorbonne Universites, 
      UPMC University Paris 06, UMR S 1138, Paris, F-75006, France; Universite Paris 
      Descartes, Sorbonne Paris Cite, UMR S 1138, Paris, F-75006, France. Electronic 
      address: jagadeesh.bayry@crc.jussieu.fr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20170912
PL  - England
TA  - Trends Immunol
JT  - Trends in immunology
JID - 100966032
RN  - 0 (Immunoglobulin G)
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Animals
MH  - Blood Circulation
MH  - Dendritic Cells/*metabolism
MH  - Humans
MH  - Immunization
MH  - Immunoglobulin G/*immunology
MH  - Immunoglobulins, Intravenous/*immunology/therapeutic use
MH  - Lymphocyte Activation
MH  - Mice
MH  - T-Lymphocytes, Regulatory/*immunology
OTO - NOTNLM
OT  - DC-SIGN
OT  - DCIR
OT  - IL-33
OT  - antibody
OT  - dendritic cells
OT  - intravenous immunoglobulin
OT  - prostaglandin E2
OT  - regulatory T cells
OT  - tregitopes
EDAT- 2017/09/17 06:00
MHDA- 2018/06/13 06:00
CRDT- 2017/09/17 06:00
PHST- 2017/07/03 00:00 [received]
PHST- 2017/08/07 00:00 [revised]
PHST- 2017/08/25 00:00 [accepted]
PHST- 2017/09/17 06:00 [pubmed]
PHST- 2018/06/13 06:00 [medline]
PHST- 2017/09/17 06:00 [entrez]
AID - S1471-4906(17)30172-2 [pii]
AID - 10.1016/j.it.2017.08.008 [doi]
PST - ppublish
SO  - Trends Immunol. 2017 Nov;38(11):789-792. doi: 10.1016/j.it.2017.08.008. Epub 2017 
      Sep 12.