PMID- 28918102 OWN - NLM STAT- MEDLINE DCOM- 20190117 LR - 20220317 IS - 1532-821X (Electronic) IS - 0003-9993 (Linking) VI - 99 IP - 3 DP - 2018 Mar TI - Minimal Clinically Important Difference for the Rasch Neuropsychiatric Inventory Irritability and Aggression Scale for Traumatic Brain Injury. PG - 603-606.e1 LID - S0003-9993(17)31081-X [pii] LID - 10.1016/j.apmr.2017.06.038 [doi] AB - OBJECTIVE: To determine the minimal clinically important difference (MCID) for a Rasch measure derived from the Irritability/Lability and Agitation/Aggression subscales of the Neuropsychiatric Inventory (NPI)-the Rasch NPI Irritability and Aggression Scale for Traumatic Brain Injury (NPI-TBI-IA). DESIGN: Distribution-based statistical methods were applied to retrospective data to determine candidates for the MCID. These candidates were evaluated by anchoring the NPI-TBI-IA to Global Impression of Change (GIC) ratings by participants, significant others, and a supervising physician. SETTING: Postacute rehabilitation outpatient clinic. PARTICIPANTS: 274 cases with observer ratings; 232 cases with self-ratings by participants with moderate-severe TBI at least 6 months postinjury. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURE: NPI-TBI-IA. RESULTS: For observer ratings on the NPI-TBI-IA, anchored comparisons found an improvement of 0.5 SD was associated with at least minimal general improvement on GIC by a significant majority (69%-80%); 0.5 SD improvement on participant NPI-TBI-IA self-ratings was also associated with at least minimal improvement on the GIC by a substantial majority (77%-83%). The percentage indicating significant global improvement did not increase markedly on most ratings at higher levels of improvement on the NPI-TBI-IA. CONCLUSIONS: A 0.5 SD improvement on the NPI-TBI-IA indicates the MCID for both observer and participant ratings on this measure. CI - Copyright (c) 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved. FAU - Malec, James F AU - Malec JF AD - Department of Physical Medicine and Rehabilitation, Indiana University School of Medicine, Indianapolis, IN; Rehabilitation Hospital of Indiana, Indianapolis, IN; Mayo Clinic, Rochester, MN. Electronic address: jfmalec@iupui.edu. FAU - Hammond, Flora M AU - Hammond FM AD - Department of Physical Medicine and Rehabilitation, Indiana University School of Medicine, Indianapolis, IN; Rehabilitation Hospital of Indiana, Indianapolis, IN. LA - eng PT - Journal Article PT - Research Support, U.S. Gov't, Non-P.H.S. PT - Research Support, U.S. Gov't, P.H.S. DEP - 20170914 PL - United States TA - Arch Phys Med Rehabil JT - Archives of physical medicine and rehabilitation JID - 2985158R SB - IM MH - Adult MH - Aggression/*psychology MH - Brain Injuries, Traumatic/*psychology MH - Female MH - Humans MH - *Irritable Mood MH - Male MH - Middle Aged MH - *Minimal Clinically Important Difference MH - Neuropsychological Tests/*statistics & numerical data MH - Retrospective Studies OTO - NOTNLM OT - Aggression OT - Behavior OT - Brain injuries OT - Rehabilitation EDAT- 2017/09/18 06:00 MHDA- 2019/01/18 06:00 CRDT- 2017/09/18 06:00 PHST- 2017/04/12 00:00 [received] PHST- 2017/06/14 00:00 [revised] PHST- 2017/06/20 00:00 [accepted] PHST- 2017/09/18 06:00 [pubmed] PHST- 2019/01/18 06:00 [medline] PHST- 2017/09/18 06:00 [entrez] AID - S0003-9993(17)31081-X [pii] AID - 10.1016/j.apmr.2017.06.038 [doi] PST - ppublish SO - Arch Phys Med Rehabil. 2018 Mar;99(3):603-606.e1. doi: 10.1016/j.apmr.2017.06.038. Epub 2017 Sep 14.