PMID- 28923027
OWN - NLM
STAT- MEDLINE
DCOM- 20180521
LR  - 20181113
IS  - 1471-2407 (Electronic)
IS  - 1471-2407 (Linking)
VI  - 17
IP  - 1
DP  - 2017 Sep 18
TI  - Aesthetic principles access thyroidectomy produces the best cosmetic outcomes as 
      assessed using the patient and observer scar assessment scale.
PG  - 654
LID - 10.1186/s12885-017-3645-2 [doi]
LID - 654
AB  - BACKGROUND: Thyroid carcinoma (TC) is more likely to occur in young women. The 
      aim of this study was to compare the aesthetic effect of different 
      thyroidectomies. METHODS: One hundred twenty female patients who underwent 
      thyroidectomy were evenly distributed into three groups: conventional access 
      (CA), aesthetic principles access (APA) and minimally invasive access (MIA). The 
      Patient and Observer Scar Assessment Scale (POSAS) was used as the assessment 
      tool for the linear scar. RESULTS: The patients in the MIA group showed 
      significantly less intraoperative blood loss, less drainage, a shorter scar 
      length and a shorter duration of drainage than those in the CA group and the APA 
      group. However, the operation time of 129.0 min in the MIA group was 
      significantly longer than the 79.6 min in the CA group and the 77.0 min in the 
      APA group. The best aesthetic score, as assessed by the Observer Scar Assessment 
      Scale (OSAS), was obtained in the APA group. The Patient Scar Assessment Scale 
      (PSAS) scores were significantly lower in the APA group and CA group than in the 
      MIA group. Significantly lower objective scar ratings were found in the APA group 
      than in the other two groups. CONCLUSION: These results show that APA produced 
      the best surgical outcomes in TC patients, indicating that conventional 
      thyroidectomy can produce an ideal aesthetic result using the principles of 
      aesthetic surgery. Thyroid surgery need not be performed through excessively 
      short incisions for the sake of patient satisfaction with the scar's appearance. 
      TRIAL REGISTRATION: This clinical trial was retrospectively registered on 
      ClinicalTrials.gov PRS on August 1st,2017 ( NCT03239769 ).
FAU - Ma, Xiao
AU  - Ma X
AUID- ORCID: 0000-0002-2465-4151
AD  - Department of Head and Neck, Perking University Cancer Hospital and Institute, 52 
      Fucheng Road, Haidian District, Beijing, China. madaxiao@qq.com.
AD  - Key Laboratory of Carcinogenesis and Translational Research, Department of Head 
      and Neck, Perking University Cancer Hospital and Institute, Beijing, 100142, 
      China. madaxiao@qq.com.
FAU - Xia, Qi-Jun
AU  - Xia QJ
AD  - Department of General Surgery, PLA Rocket General Hospital, 16 Xinjiekouwai 
      Street, Xicheng District, Beijing, China.
FAU - Li, Guojun
AU  - Li G
AD  - Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer 
      Center, 1515 Holcombe Blvd, Houston, TX, USA.
AD  - Department of Epidemiology, The University of Texas MD Anderson Cancer Center, 
      1515 Holcombe Blvd, Houston, TX, USA.
FAU - Wang, Tian-Xiao
AU  - Wang TX
AD  - Department of Head and Neck, Perking University Cancer Hospital and Institute, 52 
      Fucheng Road, Haidian District, Beijing, China.
FAU - Li, Qin
AU  - Li Q
AD  - Department of Oncology, Beijing Friendship Hospital, Capital Medical University, 
      95 Yongan Raod, Xicheng District, Beijing, 100050, China.
LA  - eng
SI  - ClinicalTrials.gov/NCT03239769
PT  - Journal Article
DEP - 20170918
PL  - England
TA  - BMC Cancer
JT  - BMC cancer
JID - 100967800
SB  - IM
MH  - Adult
MH  - Cicatrix/*pathology
MH  - Esthetics
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Observer Variation
MH  - Patient Satisfaction
MH  - Retrospective Studies
MH  - Surveys and Questionnaires
MH  - Thyroid Neoplasms/*surgery
MH  - Thyroidectomy
MH  - Treatment Outcome
PMC - PMC5604280
OTO - NOTNLM
OT  - Aesthetic principle
OT  - Minimally invasive access
OT  - POSAS
OT  - Thyroid surgery
OT  - Thyroidectomy
COIS- ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The research was reviewed and 
      approved by the Ethics Committee of Peking University Cancer Hospital. All 
      procedures performed in the study involving human participants were in accordance 
      with the ethical standards of Peking University Cancer Hospital and/or the 
      national research committee, as well as the 1964 Helsinki Declaration and its 
      later amendments or comparable ethical standards. Before collecting human 
      samples, all participants signed informed consent forms according to our 
      institutional guidelines. CONSENT FOR PUBLICATION: Written informed consent for 
      publication of their clinical details and/or clinical images was obtained from 
      the patient/parent/guardian/ relative of the patient. A copy of the consent form 
      is available for review by the Editor of this journal. COMPETING INTERESTS: The 
      authors declare that they have no competing interests. PUBLISHER'S NOTE: Springer 
      Nature remains neutral with regard to jurisdictional claims in published maps and 
      institutional affiliations.
EDAT- 2017/09/20 06:00
MHDA- 2018/05/22 06:00
PMCR- 2017/09/18
CRDT- 2017/09/20 06:00
PHST- 2016/12/27 00:00 [received]
PHST- 2017/09/13 00:00 [accepted]
PHST- 2017/09/20 06:00 [entrez]
PHST- 2017/09/20 06:00 [pubmed]
PHST- 2018/05/22 06:00 [medline]
PHST- 2017/09/18 00:00 [pmc-release]
AID - 10.1186/s12885-017-3645-2 [pii]
AID - 3645 [pii]
AID - 10.1186/s12885-017-3645-2 [doi]
PST - epublish
SO  - BMC Cancer. 2017 Sep 18;17(1):654. doi: 10.1186/s12885-017-3645-2.