PMID- 28925257
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20180730
LR  - 20180730
IS  - 1944-8252 (Electronic)
IS  - 1944-8244 (Linking)
VI  - 9
IP  - 38
DP  - 2017 Sep 27
TI  - Flexible Microsphere-Embedded Film for Microsphere-Enhanced Raman Spectroscopy.
PG  - 32896-32906
LID - 10.1021/acsami.7b09884 [doi]
AB  - Dielectric microspheres with extraordinary microscale optical properties, such as 
      photonic nanojets, optical whispering-gallery modes (WGMs), and directional 
      antennas, have drawn interest in many research fields. Microsphere-enhanced Raman 
      spectroscopy (MERS) is an alternative approach for enhanced Raman detection by 
      dielectric microstructures. Unfortunately, fabrication of microsphere monolayer 
      arrays is the major challenge of MERS for practical applications on various 
      specimen surfaces. Here we report a microsphere-embedded film (MF) by immersing a 
      highly refractive microsphere monolayer array in the poly(dimethylsiloxane) 
      (PDMS) film as a flexible MERS sensing platform for one- to three-dimensional (1D 
      to 3D) specimen surfaces. The directional antennas and wave-guided 
      whispering-gallery modes (WG-WGMs) contribute to the majority of Raman 
      enhancement by the MFs. Moreover, the MF can be coupled with surface-enhanced 
      Raman spectroscopy (SERS) to provide an extra >10-fold enhancement. The limit of 
      detection is therefore improved for sensing of crystal violet (CV) and Sudan I 
      molecules in aqueous solutions at concentrations down to 10(-7) M. A hybrid 
      dual-layer microsphere enhancer, constructed by depositing a MF onto a 
      microsphere monolayer array, is also demonstrated, wherein the WG-WGMs become 
      dominant and boost the enhancement ratio >50-fold. The present work opens up new 
      opportunities for design of cost-effective and flexible MERS sensing platforms as 
      individual or associated techniques toward practical applications in 
      ultrasensitive Raman detection.
FAU - Xing, Cheng
AU  - Xing C
FAU - Yan, Yinzhou
AU  - Yan Y
AUID- ORCID: 0000-0002-1969-7878
FAU - Feng, Chao
AU  - Feng C
FAU - Xu, Jiayu
AU  - Xu J
FAU - Dong, Peng
AU  - Dong P
AD  - Capital Aerospace Machinery Company , Beijing 100076, China.
FAU - Guan, Wei
AU  - Guan W
FAU - Zeng, Yong
AU  - Zeng Y
FAU - Zhao, Yan
AU  - Zhao Y
FAU - Jiang, Yijian
AU  - Jiang Y
LA  - eng
PT  - Journal Article
DEP - 20170919
PL  - United States
TA  - ACS Appl Mater Interfaces
JT  - ACS applied materials & interfaces
JID - 101504991
OTO - NOTNLM
OT  - PDMS film
OT  - dielectric microsphere
OT  - flexible Raman enhancer
OT  - microsphere-enhanced Raman spectroscopy
OT  - surface-enhanced Raman spectroscopy
EDAT- 2017/09/20 06:00
MHDA- 2017/09/20 06:01
CRDT- 2017/09/20 06:00
PHST- 2017/09/20 06:00 [pubmed]
PHST- 2017/09/20 06:01 [medline]
PHST- 2017/09/20 06:00 [entrez]
AID - 10.1021/acsami.7b09884 [doi]
PST - ppublish
SO  - ACS Appl Mater Interfaces. 2017 Sep 27;9(38):32896-32906. doi: 
      10.1021/acsami.7b09884. Epub 2017 Sep 19.