PMID- 28928997
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2090-6625 (Print)
IS  - 2090-6633 (Electronic)
VI  - 2017
DP  - 2017
TI  - Neurosyphilis with Concomitant Cryptococcal and Tuberculous Meningitis in a 
      Patient with AIDS: Report of a Unique Case.
PG  - 4103858
LID - 10.1155/2017/4103858 [doi]
LID - 4103858
AB  - Meningitis in individuals living with acquired immunodeficiency syndrome (AIDS) 
      is most frequently infectious in origin and usually due to opportunistic 
      infections. The most common pathogens are Cryptococcus neoformans and 
      Mycobacterium tuberculosis. Treponema pallidum causes neurosyphilis and can 
      complicate HIV infections at any time after the initial infection. Simultaneous 
      infections of the central nervous system caused by these pathogens are very 
      uncommon even in the setting of severe immunosuppression. We report the case of a 
      newly diagnosed HIV/AIDS young man who was found to have neurosyphilis with 
      Cryptococcus meningitis. After a few weeks of treatment and initiation of 
      antiretroviral therapy, he was also diagnosed with tuberculous meningitis, which 
      was probably unmasked by the development of immune reconstitution inflammatory 
      syndrome (IRIS). To the best of our knowledge, this is the only case of reported 
      neurosyphilis and meningitis caused concomitantly by Cryptococcus and 
      Mycobacterium tuberculosis.
FAU - Gonzales Zamora, Jose Armando
AU  - Gonzales Zamora JA
AUID- ORCID: 0000-0002-2768-9712
AD  - Division of Infectious Diseases, Department of Medicine, University of Miami, 
      Miller School of Medicine, Miami, FL 33136, USA.
FAU - Espinoza, Luis Alberto
AU  - Espinoza LA
AD  - Division of Infectious Diseases, Department of Medicine, University of Miami, 
      Miller School of Medicine, Miami, FL 33136, USA.
FAU - Nwanyanwu, Rita N
AU  - Nwanyanwu RN
AD  - Division of Infectious Diseases, Department of Medicine, University of Miami, 
      Miller School of Medicine, Miami, FL 33136, USA.
LA  - eng
PT  - Case Reports
DEP - 20170827
PL  - Egypt
TA  - Case Rep Infect Dis
JT  - Case reports in infectious diseases
JID - 101573243
PMC - PMC5591983
EDAT- 2017/09/21 06:00
MHDA- 2017/09/21 06:01
PMCR- 2017/08/27
CRDT- 2017/09/21 06:00
PHST- 2017/06/07 00:00 [received]
PHST- 2017/07/30 00:00 [revised]
PHST- 2017/07/31 00:00 [accepted]
PHST- 2017/09/21 06:00 [entrez]
PHST- 2017/09/21 06:00 [pubmed]
PHST- 2017/09/21 06:01 [medline]
PHST- 2017/08/27 00:00 [pmc-release]
AID - 10.1155/2017/4103858 [doi]
PST - ppublish
SO  - Case Rep Infect Dis. 2017;2017:4103858. doi: 10.1155/2017/4103858. Epub 2017 Aug 
      27.