PMID- 28943533
OWN - NLM
STAT- MEDLINE
DCOM- 20190813
LR  - 20190813
IS  - 1347-4820 (Electronic)
IS  - 1346-9843 (Linking)
VI  - 82
IP  - 5
DP  - 2018 Apr 25
TI  - Incidence and Significance of Spontaneous ST Segment Re-elevation After 
      Reperfused Anterior Acute Myocardial Infarction　- Relationship With Infarct Size, 
      Adverse Remodeling, and Events at 1 Year.
PG  - 1379-1386
LID - 10.1253/circj.CJ-17-0671 [doi]
AB  - BACKGROUND: Up to 25% of patients with ST elevation myocardial infarction (STEMI) 
      have ST segment re-elevation after initial regression post-reperfusion and there 
      are few data regarding its prognostic significance.Methods and Results:A standard 
      12-lead electrocardiogram (ECG) was recorded in 662 patients with anterior STEMI 
      referred for primary percutaneous coronary intervention (PPCI). ECGs were 
      recorded 60-90 min after PPCI and at discharge. ST segment re-elevation was 
      defined as a >/=0.1-mV increase in STMax between the post-PPCI and discharge ECGs. 
      Infarct size (assessed as creatine kinase [CK] peak), echocardiography at 
      baseline and follow-up, and all-cause death and heart failure events at 1 year 
      were assessed. In all, 128 patients (19%) had ST segment re-elevation. There was 
      no difference between patients with and without re-elevation in infarct size (CK 
      peak [mean+/-SD] 4,231+/-2,656 vs. 3,993+/-2,819 IU/L; P=0.402), left ventricular (LV) 
      ejection fraction (50.7+/-11.6% vs. 52.2+/-10.8%; P=0.186), LV adverse remodeling 
      (20.1+/-38.9% vs. 18.3+/-30.9%; P=0.631), or all-cause mortality and heart failure 
      events (22 [19.8%] vs. 106 [19.2%]; P=0.887) at 1 year. CONCLUSIONS: Among 
      anterior STEMI patients treated by PPCI, ST segment re-elevation was present in 
      19% and was not associated with increased infarct size or major adverse events at 
      1 year.
FAU - Cuenin, Leo
AU  - Cuenin L
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
FAU - Lamoureux, Sophie
AU  - Lamoureux S
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
FAU - Schaaf, Mathieu
AU  - Schaaf M
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
FAU - Bochaton, Thomas
AU  - Bochaton T
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
FAU - Monassier, Jean-Pierre
AU  - Monassier JP
AD  - Centre Hospitalier de Mulhouse.
FAU - Claeys, Marc J
AU  - Claeys MJ
AD  - Hopitaux Universitaires de Strasbourg.
FAU - Rioufol, Gilles
AU  - Rioufol G
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
FAU - Finet, Gerard
AU  - Finet G
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
FAU - Garcia-Dorado, David
AU  - Garcia-Dorado D
AD  - Hospital Universitari Vall d'Hebron.
FAU - Angoulvant, Denis
AU  - Angoulvant D
AD  - Centre Hospitalier Regional Universitaire de Tours.
FAU - Elbaz, Meyer
AU  - Elbaz M
AD  - Centre Hospitalier Universitaire de Rangueil.
FAU - Delarche, Nicolas
AU  - Delarche N
AD  - Centre Hospitalier de Pau.
FAU - Coste, Pierre
AU  - Coste P
AD  - Hopital Haut Leveque.
FAU - Metge, Marc
AU  - Metge M
AD  - Hopital Henri Duffau.
FAU - Perret, Thibault
AU  - Perret T
AD  - Centre Hospitalier Saint-Joseph et Saint-Luc.
FAU - Motreff, Pascal
AU  - Motreff P
AD  - Hopital Gabriel Montpied.
FAU - Bonnefoy-Cudraz, Eric
AU  - Bonnefoy-Cudraz E
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
FAU - Vanzetto, Gerald
AU  - Vanzetto G
AD  - Centre Hospitalier Universitaire de Grenoble.
FAU - Morel, Olivier
AU  - Morel O
AD  - University Hospital Antwerp.
FAU - Boussaha, Inesse
AU  - Boussaha I
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
FAU - Ovize, Michel
AU  - Ovize M
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
FAU - Mewton, Nathan
AU  - Mewton N
AD  - Hopital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
DEP - 20170923
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
RN  - EC 2.7.3.2 (Creatine Kinase)
CIN - Circ J. 2018 Apr 25;82(5):1249-1250. PMID: 29618680
MH  - Aged
MH  - *Anterior Wall Myocardial Infarction/blood/physiopathology/surgery
MH  - Creatine Kinase/blood
MH  - *Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/blood/physiopathology/surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Percutaneous Coronary Intervention
MH  - Prospective Studies
MH  - *ST Elevation Myocardial Infarction/blood/physiopathology/surgery
MH  - *Stroke Volume
MH  - *Ventricular Function, Left
MH  - Ventricular Remodeling
OTO - NOTNLM
OT  - Reperfusion syndrome
OT  - ST segment elevation myocardial infarction
OT  - ST segment re-elevation
OT  - ST segment regression
EDAT- 2017/09/26 06:00
MHDA- 2019/08/14 06:00
CRDT- 2017/09/26 06:00
PHST- 2017/09/26 06:00 [pubmed]
PHST- 2019/08/14 06:00 [medline]
PHST- 2017/09/26 06:00 [entrez]
AID - 10.1253/circj.CJ-17-0671 [doi]
PST - ppublish
SO  - Circ J. 2018 Apr 25;82(5):1379-1386. doi: 10.1253/circj.CJ-17-0671. Epub 2017 Sep 
      23.