PMID- 28943556
OWN - NLM
STAT- MEDLINE
DCOM- 20180425
LR  - 20181202
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Print)
IS  - 0918-2918 (Linking)
VI  - 56
IP  - 21
DP  - 2017 Nov 1
TI  - Central Diabetes Insipidus in Refractory Antineutrophil Cytoplasmic 
      Antibody-associated Vasculitis.
PG  - 2943-2948
LID - 10.2169/internalmedicine.8683-16 [doi]
AB  - We herein describe two cases of refractory antineutrophil cytoplasmic 
      antibody-associated vasculitis (AAV) complicated with diabetes insipidus (DI) 
      possibly related to hypertrophic pachymeningitis (HP). One patient had 
      microscopic polyangiitis and HP, which were refractory to cyclophosphamide, 
      azathioprine, rituximab, mycophenolate mofetil (MMF), and mizoribine. Remission 
      was finally achieved with the use of etanercept, but DI occurred 5 years later. 
      The other patient had granulomatosis with polyangiitis, which that was refractory 
      to cyclophosphamide, methotrexate, MMF, and rituximab. DI subsequently developed, 
      but was successfully treated with etanercept. Dura mater hypertrophy was 
      macroscopically observed in the latter case.
FAU - Ohashi, Keiji
AU  - Ohashi K
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Morishita, Michiko
AU  - Morishita M
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Watanabe, Haruki
AU  - Watanabe H
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Sada, Ken-Ei
AU  - Sada KE
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Katsuyama, Takayuki
AU  - Katsuyama T
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Miyawaki, Yoshia
AU  - Miyawaki Y
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Katsuyama, Eri
AU  - Katsuyama E
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Narazaki, Mariko
AU  - Narazaki M
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Tatebe, Noriko
AU  - Tatebe N
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Watanabe, Katsue
AU  - Watanabe K
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Kawabata, Tomoko
AU  - Kawabata T
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
FAU - Wada, Jun
AU  - Wada J
AD  - Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama 
      University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 
      Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20170925
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (Immunosuppressive Agents)
RN  - OP401G7OJC (Etanercept)
SB  - IM
MH  - Aged
MH  - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/*complications/*drug 
      therapy
MH  - Diabetes Insipidus/*complications
MH  - Etanercept/*therapeutic use
MH  - Female
MH  - Humans
MH  - Immunosuppressive Agents/*therapeutic use
MH  - Meningitis/complications
MH  - Microscopic Polyangiitis/complications
PMC - PMC5709644
OTO - NOTNLM
OT  - antineutrophil cytoplasmic antibody-associated vasculitis
OT  - diabetes insipidus
OT  - etanercept
OT  - hypertrophic pachymeningitis
OT  - rituximab
EDAT- 2017/09/26 06:00
MHDA- 2018/04/26 06:00
PMCR- 2017/11/01
CRDT- 2017/09/26 06:00
PHST- 2017/09/26 06:00 [pubmed]
PHST- 2018/04/26 06:00 [medline]
PHST- 2017/09/26 06:00 [entrez]
PHST- 2017/11/01 00:00 [pmc-release]
AID - 10.2169/internalmedicine.8683-16 [doi]
PST - ppublish
SO  - Intern Med. 2017 Nov 1;56(21):2943-2948. doi: 10.2169/internalmedicine.8683-16. 
      Epub 2017 Sep 25.