PMID- 28944197
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2222-3959 (Print)
IS  - 2227-4898 (Electronic)
IS  - 2222-3959 (Linking)
VI  - 10
IP  - 9
DP  - 2017
TI  - Influence of corneal power on circumpapillary retinal nerve fiber layer and optic 
      nerve head measurements by spectral-domain optical coherence tomography.
PG  - 1385-1391
LID - 10.18240/ijo.2017.09.09 [doi]
AB  - AIM: To evaluate the influence of corneal power on circumpapillary retinal nerve 
      fiber layer (cpRNFL) and optic nerve head (ONH) measurements by spectral-domain 
      optical coherence tomography (SD-OCT). METHODS: Twenty-five eyes of 25 healthy 
      participants (mean age 23.6+/-3.6y) were imaged by SD-OCT using horizontal raster 
      scans. Disposable soft contact lenses of different powers (from -11 to +5 
      diopters including 0 diopter) were worn to induce 2-diopter changes in corneal 
      power. Differences in the cpRNFL and ONH measurements per diopter of change in 
      corneal power were analyzed. RESULTS: As corneal power increased by 1 diopter, 
      total and quadrant cpRNFL thicknesses, except for the nasal sector, decreased by 
      --0.19 to -0.32 microm (P<0.01). Furthermore, the disc, cup, and rim areas decreased 
      by -0.017, -0.007, and -0.015 mm(2), respectively (P<0.001); the cup and rim 
      volumes decreased by -0.0013 and -0.006 mm(3), respectively (P<0.01); and the 
      vertical and horizontal disc diameters decreased by -0.006 and -0.007 mm, 
      respectively (P<0.001). CONCLUSION: For more precise OCT imaging, the ocular 
      magnification should be corrected by considering both the axial length and 
      corneal power. However, the effect of corneal power changes on cpRNFL thickness 
      and ONH topography are small when compare with those of the axial length.
FAU - Hirasawa, Kazunori
AU  - Hirasawa K
AD  - Department of Orthoptics and Visual Science, School of Allied Health Sciences, 
      Kitasato University, Sagamihara, Kanagawa 252-0373, Japan.
FAU - Shoji, Nobuyuki
AU  - Shoji N
AD  - Department of Ophthalmology, School of medicine, Kitasato University, Sagamihara, 
      Kanagawa 252-0373, Japan.
LA  - eng
PT  - Journal Article
DEP - 20170918
PL  - China
TA  - Int J Ophthalmol
JT  - International journal of ophthalmology
JID - 101553860
PMC - PMC5596223
OTO - NOTNLM
OT  - circumpapillary retinal nerve fiber layer
OT  - corneal power
OT  - ocular magnification
OT  - optic nerve head
OT  - optical coherence tomography
EDAT- 2017/09/26 06:00
MHDA- 2017/09/26 06:01
PMCR- 2017/09/18
CRDT- 2017/09/26 06:00
PHST- 2017/02/24 00:00 [received]
PHST- 2017/04/24 00:00 [accepted]
PHST- 2017/09/26 06:00 [entrez]
PHST- 2017/09/26 06:00 [pubmed]
PHST- 2017/09/26 06:01 [medline]
PHST- 2017/09/18 00:00 [pmc-release]
AID - ijo-10-09-1385 [pii]
AID - 10.18240/ijo.2017.09.09 [doi]
PST - epublish
SO  - Int J Ophthalmol. 2017 Sep 18;10(9):1385-1391. doi: 10.18240/ijo.2017.09.09. 
      eCollection 2017.