PMID- 28944272
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231104
IS  - 2332-8940 (Print)
IS  - 2332-8959 (Electronic)
IS  - 2332-8940 (Linking)
VI  - 4
IP  - 3
DP  - 2017
TI  - The effect of environmental temperature on exercise-dependent release of 
      brain-derived neurotrophic factor.
PG  - 305-313
LID - 10.1080/23328940.2017.1328304 [doi]
AB  - Brain-derived neurotrophic factor (BDNF) is a biomarker of cognitive function 
      that is released into the blood stream following exercise, and cognitive function 
      is impaired by environmental temperatures that are hot and cold. Purpose: To 
      evaluate the exercise-dependent release of BDNF in different environmental 
      temperatures. Methods: Recreationally trained males each completed three trials 
      consisting of cycling for 1 h at 60% W(max) at three different temperatures: 33 degrees C 
      (hot), 7 degrees C (cold), and 20 degrees C (moderate room temperature). Blood was taken from the 
      antecubital vein pre-exercise, immediately post-exercise, and 3 h post-exercise. 
      Respiratory gases were collected periodically throughout exercise and recovery. 
      Results: BDNF was elevated immediately following an exercise bout (1711 +/- 766 
      pg.ml(-1)) regardless of temperature from pre-exercise (1257 +/- 653 pg.ml(-1), p = 
      0.001) and returned to basal levels following 3 h of recovery (1289 +/- 650 
      pg.ml(-1), p = 0.786). There was no effect (p > 0.05) of temperature on BDNF 
      following the exercise bout. Plasma glucose was elevated in hot (6.2 +/- 0.9 mmol) 
      over cold (5.3 +/- 0.6 mmol, p = 0.035) and moderate room temperature (5.2 +/- 0.5, p 
      = 0.008). VO(2) was elevated during exercise in hot (3.01 +/- 0.45 L.min(-1)) over 
      cold (2.67 +/- 0.35 L.min(-1), p = 0.005) and moderate room temperature (2.80 +/- 
      0.38 L.min(-1), p = 0.001). There was no relationship between BDNF and plasma 
      glucose (p > 0.05) or VO(2) across any time point or temperature (p > 0.05). 
      Conclusion: With aerobic exercise, BDNF is elevated; however, the release of BDNF 
      is not impacted by different environmental temperatures during exercise.
FAU - Collins, Christopher W
AU  - Collins CW
AD  - Exercise Physiology Laboratory, University of Nebraska at Omaha, Omaha, NE, USA.
FAU - Shute, Robert J
AU  - Shute RJ
AD  - Exercise Physiology Laboratory, University of Nebraska at Omaha, Omaha, NE, USA.
FAU - Heesch, Matthew W S
AU  - Heesch MWS
AD  - Exercise Physiology Laboratory, University of Nebraska at Omaha, Omaha, NE, USA.
FAU - Slivka, Dustin R
AU  - Slivka DR
AD  - Exercise Physiology Laboratory, University of Nebraska at Omaha, Omaha, NE, USA.
LA  - eng
GR  - P20 GM103427/GM/NIGMS NIH HHS/United States
PT  - Journal Article
DEP - 20170522
PL  - United States
TA  - Temperature (Austin)
JT  - Temperature (Austin, Tex.)
JID - 101655855
PMC - PMC5605157
OTO - NOTNLM
OT  - BDNF
OT  - ELISA
OT  - cycling
OT  - exercise
OT  - glucose
OT  - heat
EDAT- 2017/09/26 06:00
MHDA- 2017/09/26 06:01
PMCR- 2018/05/22
CRDT- 2017/09/26 06:00
PHST- 2017/01/26 00:00 [received]
PHST- 2017/04/24 00:00 [revised]
PHST- 2017/05/05 00:00 [accepted]
PHST- 2017/09/26 06:00 [entrez]
PHST- 2017/09/26 06:00 [pubmed]
PHST- 2017/09/26 06:01 [medline]
PHST- 2018/05/22 00:00 [pmc-release]
AID - 1328304 [pii]
AID - 10.1080/23328940.2017.1328304 [doi]
PST - epublish
SO  - Temperature (Austin). 2017 May 22;4(3):305-313. doi: 
      10.1080/23328940.2017.1328304. eCollection 2017.