PMID- 28946670 OWN - NLM STAT- MEDLINE DCOM- 20180604 LR - 20221207 IS - 2072-6643 (Electronic) IS - 2072-6643 (Linking) VI - 9 IP - 10 DP - 2017 Sep 25 TI - Relative Validity and Reproducibility of a Food Frequency Questionnaire for Assessing Dietary Intakes in a Multi-Ethnic Asian Population Using 24-h Dietary Recalls and Biomarkers. LID - 10.3390/nu9101059 [doi] LID - 1059 AB - The assessment of diets in multi-ethnic cosmopolitan settings is challenging. A semi-quantitative 163-item food frequency questionnaire (FFQ) was developed for the adult Singapore population, and this study aimed to assess its reproducibility and relative validity against 24-h dietary recalls (24 h DR) and biomarkers. The FFQ was administered twice within a six-month interval in 161 adults (59 Chinese, 46 Malay, and 56 Indian). Fasting plasma, overnight urine, and 24 h DR were collected after one month and five months. Intra-class correlation coefficients between the two FFQ were above 0.70 for most foods and nutrients. The median correlation coefficient between energy-adjusted deattenuated FFQ and 24 h DR nutrient intakes was 0.40 for FFQ1 and 0.39 for FFQ2, highest for calcium and iron, and lowest for energy and carbohydrates. Significant associations were observed between urinary isoflavones and soy protein intake (r = 0.46), serum carotenoids and fruit and vegetable intake (r = 0.34), plasma eicosapentaenoic acid and docosahexaenoic acid (EPA + DHA) and fish/seafood intake (r = 0.36), and plasma odd chain saturated fatty acids (SFA) and dairy fat intake (r = 0.25). Associations between plasma EPA + DHA and fish/seafood intake were consistent across ethnic groups (r = 0.28-0.49), while differences were observed for other associations. FFQ assessment of dietary intakes in modern cosmopolitan populations remains feasible for the purpose of ranking individuals' dietary exposures in epidemiological studies. FAU - Whitton, Clare AU - Whitton C AD - Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore. clarewhitton@nus.edu.sg. FAU - Ho, Jolene Chien Yee AU - Ho JCY AD - Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore. ephjhcy@nus.edu.sg. FAU - Tay, Zoey AU - Tay Z AD - Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore. tayzoey@nus.edu.sg. FAU - Rebello, Salome A AU - Rebello SA AD - Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore. ephsar@nus.edu.sg. FAU - Lu, Yonghai AU - Lu Y AD - Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore. ephluyng@nus.edu.sg. FAU - Ong, Choon Nam AU - Ong CN AD - Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore. ephocn@nus.edu.sg. FAU - van Dam, Rob M AU - van Dam RM AD - Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore. rob.van.dam@nus.edu.sg. AD - Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore 119228, Singapore. rob.van.dam@nus.edu.sg. AD - Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. rob.van.dam@nus.edu.sg. LA - eng PT - Journal Article PT - Validation Study DEP - 20170925 PL - Switzerland TA - Nutrients JT - Nutrients JID - 101521595 RN - 0 (Biomarkers) SB - IM MH - Adolescent MH - Adult MH - Aged MH - *Asian People MH - Biomarkers/blood/urine MH - China/ethnology MH - Diet/*ethnology MH - *Diet Records MH - Feeding Behavior/*ethnology MH - Female MH - Humans MH - India/ethnology MH - Malaysia/ethnology MH - Male MH - Middle Aged MH - *Nutrition Assessment MH - Nutritional Status/*ethnology MH - Predictive Value of Tests MH - Reproducibility of Results MH - Singapore/epidemiology MH - *Surveys and Questionnaires MH - Time Factors MH - Young Adult PMC - PMC5691676 OTO - NOTNLM OT - 24-h dietary recall OT - Asia OT - biomarkers OT - carotenoids OT - food frequency questionnaire OT - isoflavones OT - multi-ethnic OT - plasma fatty acids OT - validation COIS- The authors declare no conflict of interest. EDAT- 2017/09/28 06:00 MHDA- 2018/06/05 06:00 PMCR- 2017/10/01 CRDT- 2017/09/27 06:00 PHST- 2017/08/25 00:00 [received] PHST- 2017/09/15 00:00 [revised] PHST- 2017/09/19 00:00 [accepted] PHST- 2017/09/27 06:00 [entrez] PHST- 2017/09/28 06:00 [pubmed] PHST- 2018/06/05 06:00 [medline] PHST- 2017/10/01 00:00 [pmc-release] AID - nu9101059 [pii] AID - nutrients-09-01059 [pii] AID - 10.3390/nu9101059 [doi] PST - epublish SO - Nutrients. 2017 Sep 25;9(10):1059. doi: 10.3390/nu9101059.